2c8c

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m (Protected "2c8c" [edit=sysop:move=sysop])
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[[Image:2c8c.png|left|200px]]
 
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{{STRUCTURE_2c8c| PDB=2c8c | SCENE= }}
{{STRUCTURE_2c8c| PDB=2c8c | SCENE= }}
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===STRUCTURE OF THE ARTT MOTIF Q212A MUTANT C3BOT1 EXOENZYME (NAD-BOUND STATE, CRYSTAL FORM I)===
===STRUCTURE OF THE ARTT MOTIF Q212A MUTANT C3BOT1 EXOENZYME (NAD-BOUND STATE, CRYSTAL FORM I)===
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{{ABSTRACT_PUBMED_18369192}}
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==Function==
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[[http://www.uniprot.org/uniprot/ARC3_CBDP ARC3_CBDP]] ADP-ribosylates eukaryotic Rho and Rac proteins on an asparagine residue.
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{{ABSTRACT_PUBMED_18369192}}
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==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:018369192</ref><ref group="xtra">PMID:012029083</ref><references group="xtra"/>
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<ref group="xtra">PMID:018369192</ref><ref group="xtra">PMID:012029083</ref><references group="xtra"/><references/>
[[Category: Clostridium botulinum]]
[[Category: Clostridium botulinum]]
[[Category: Boquet, P.]]
[[Category: Boquet, P.]]
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[[Category: Menez, A.]]
[[Category: Menez, A.]]
[[Category: Stura, E A.]]
[[Category: Stura, E A.]]
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[[Category: Artt motif]]
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[[Category: Bacterial toxin]]
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[[Category: C3 exoenzyme]]
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[[Category: Glycosyltransferase]]
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[[Category: Transferase]]

Revision as of 23:14, 10 April 2013

Template:STRUCTURE 2c8c

Contents

STRUCTURE OF THE ARTT MOTIF Q212A MUTANT C3BOT1 EXOENZYME (NAD-BOUND STATE, CRYSTAL FORM I)

Template:ABSTRACT PUBMED 18369192

Function

[ARC3_CBDP] ADP-ribosylates eukaryotic Rho and Rac proteins on an asparagine residue.

About this Structure

2c8c is a 4 chain structure with sequence from Clostridium botulinum. Full crystallographic information is available from OCA.

Reference

  • Menetrey J, Flatau G, Boquet P, Menez A, Stura EA. Structural basis for the NAD-hydrolysis mechanism and the ARTT-loop plasticity of C3 exoenzymes. Protein Sci. 2008 May;17(5):878-86. Epub 2008 Mar 27. PMID:18369192 doi:10.1110/ps.073398508
  • Menetrey J, Flatau G, Stura EA, Charbonnier JB, Gas F, Teulon JM, Le Du MH, Boquet P, Menez A. NAD binding induces conformational changes in Rho ADP-ribosylating clostridium botulinum C3 exoenzyme. J Biol Chem. 2002 Aug 23;277(34):30950-7. Epub 2002 May 23. PMID:12029083 doi:10.1074/jbc.M201844200

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OCA

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