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3mcv
From Proteopedia
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===Structure of PTR1 from Trypanosoma brucei in ternary complex with 2,4-diamino-5-[2-(2,5-dimethoxyphenyl)ethyl]thieno[2,3-d]-pyrimidine and NADP+=== | ===Structure of PTR1 from Trypanosoma brucei in ternary complex with 2,4-diamino-5-[2-(2,5-dimethoxyphenyl)ethyl]thieno[2,3-d]-pyrimidine and NADP+=== | ||
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==Reference== | ==Reference== | ||
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[[Category: Pteridine reductase]] | [[Category: Pteridine reductase]] | ||
[[Category: Trypanosoma brucei brucei]] | [[Category: Trypanosoma brucei brucei]] | ||
[[Category: Hunter, W N.]] | [[Category: Hunter, W N.]] | ||
[[Category: Tulloch, L B.]] | [[Category: Tulloch, L B.]] | ||
| + | [[Category: Antifolate]] | ||
| + | [[Category: Oxidoreductase]] | ||
| + | [[Category: Pteridine reductase]] | ||
Revision as of 23:16, 10 April 2013
Structure of PTR1 from Trypanosoma brucei in ternary complex with 2,4-diamino-5-[2-(2,5-dimethoxyphenyl)ethyl]thieno[2,3-d]-pyrimidine and NADP+
Template:ABSTRACT PUBMED 21123874
About this Structure
3mcv is a 4 chain structure with sequence from Trypanosoma brucei brucei. Full crystallographic information is available from OCA.
Reference
- Dawson A, Tulloch LB, Barrack KL, Hunter WN. High-resolution structures of Trypanosoma brucei pteridine reductase ligand complexes inform on the placement of new molecular entities in the active site of a potential drug target. Acta Crystallogr D Biol Crystallogr. 2010 Dec;66(Pt 12):1334-40. Epub 2010, Nov 16. PMID:21123874 doi:10.1107/S0907444910040886
