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3m9q
From Proteopedia
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{{STRUCTURE_3m9q| PDB=3m9q | SCENE= }} | {{STRUCTURE_3m9q| PDB=3m9q | SCENE= }} | ||
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===Drosophila MSL3 chromodomain=== | ===Drosophila MSL3 chromodomain=== | ||
| + | {{ABSTRACT_PUBMED_20657587}} | ||
| - | + | ==Function== | |
| - | + | [[http://www.uniprot.org/uniprot/MSL3_DROME MSL3_DROME]] The MSL proteins are essential for elevating transcription of the single X chromosome in the male (X chromosome dosage compensation). Mle, msl-1 and msl-3 are colocalized on the X chromosome. Each of the MSL proteins requires all the other MSLs for wild-type X-chromosome binding.<ref>PMID:7768187</ref> | |
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==About this Structure== | ==About this Structure== | ||
| - | + | [[3m9q]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M9Q OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:020657587</ref><references group="xtra"/><references/> |
[[Category: Drosophila melanogaster]] | [[Category: Drosophila melanogaster]] | ||
[[Category: Huang, P.]] | [[Category: Huang, P.]] | ||
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[[Category: Msl3]] | [[Category: Msl3]] | ||
[[Category: Transcription upregulation]] | [[Category: Transcription upregulation]] | ||
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Revision as of 23:16, 10 April 2013
Contents |
Drosophila MSL3 chromodomain
Template:ABSTRACT PUBMED 20657587
Function
[MSL3_DROME] The MSL proteins are essential for elevating transcription of the single X chromosome in the male (X chromosome dosage compensation). Mle, msl-1 and msl-3 are colocalized on the X chromosome. Each of the MSL proteins requires all the other MSLs for wild-type X-chromosome binding.[1]
About this Structure
3m9q is a 2 chain structure with sequence from Drosophila melanogaster. Full crystallographic information is available from OCA.
Reference
- Kim D, Blus BJ, Chandra V, Huang P, Rastinejad F, Khorasanizadeh S. Corecognition of DNA and a methylated histone tail by the MSL3 chromodomain. Nat Struct Mol Biol. 2010 Aug;17(8):1027-9. Epub 2010 Jul 25. PMID:20657587 doi:10.1038/nsmb.1856
