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3mc2
From Proteopedia
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===Crystal Structure of the Murine Inhibitor of Carbonic Anhydrase=== | ===Crystal Structure of the Murine Inhibitor of Carbonic Anhydrase=== | ||
| + | {{ABSTRACT_PUBMED_20572014}} | ||
| - | + | ==Function== | |
| - | + | [[http://www.uniprot.org/uniprot/Q9DBD0_MOUSE Q9DBD0_MOUSE]] Inhibitor for carbonic anhydrase 2 (CA2). Does not bind iron ions.<ref>PMID:17511619</ref> <ref>PMID:18712936</ref> | |
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==About this Structure== | ==About this Structure== | ||
| - | + | [[3mc2]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MC2 OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:020572014</ref><references group="xtra"/><references/> |
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: Eckenroth, B E.]] | [[Category: Eckenroth, B E.]] | ||
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[[Category: Mica]] | [[Category: Mica]] | ||
[[Category: Transferrin superfamily]] | [[Category: Transferrin superfamily]] | ||
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Revision as of 23:33, 10 April 2013
Contents |
Crystal Structure of the Murine Inhibitor of Carbonic Anhydrase
Template:ABSTRACT PUBMED 20572014
Function
[Q9DBD0_MOUSE] Inhibitor for carbonic anhydrase 2 (CA2). Does not bind iron ions.[1] [2]
About this Structure
3mc2 is a 4 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.
Reference
- Eckenroth BE, Mason AB, McDevitt ME, Lambert LA, Everse SJ. The structure and evolution of the murine inhibitor of carbonic anhydrase: A member of the transferrin superfamily. Protein Sci. 2010 Jun 23. PMID:20572014 doi:10.1002/pro.439
- ↑ Wang F, Lothrop AP, James NG, Griffiths TA, Lambert LA, Leverence R, Kaltashov IA, Andrews NC, MacGillivray RT, Mason AB. A novel murine protein with no effect on iron homoeostasis is homologous with transferrin and is the putative inhibitor of carbonic anhydrase. Biochem J. 2007 Aug 15;406(1):85-95. PMID:17511619 doi:10.1042/BJ20070384
- ↑ Mason AB, Judson GL, Bravo MC, Edelstein A, Byrne SL, James NG, Roush ED, Fierke CA, Bobst CE, Kaltashov IA, Daughtery MA. Evolution reversed: the ability to bind iron restored to the N-lobe of the murine inhibitor of carbonic anhydrase by strategic mutagenesis. Biochemistry. 2008 Sep 16;47(37):9847-55. doi: 10.1021/bi801133d. Epub 2008 Aug, 20. PMID:18712936 doi:10.1021/bi801133d
