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3lpg

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[[Image:3lpg.jpg|left|200px]]
 
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{{STRUCTURE_3lpg| PDB=3lpg | SCENE= }}
{{STRUCTURE_3lpg| PDB=3lpg | SCENE= }}
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===Structure of E. coli beta-Glucuronidase bound with a novel, potent inhibitor 3-(2-fluorophenyl)-1-(2-hydroxyethyl)-1-((6-methyl-2-oxo-1,2-dihydroquinolin-3-yl)methyl)urea===
===Structure of E. coli beta-Glucuronidase bound with a novel, potent inhibitor 3-(2-fluorophenyl)-1-(2-hydroxyethyl)-1-((6-methyl-2-oxo-1,2-dihydroquinolin-3-yl)methyl)urea===
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{{ABSTRACT_PUBMED_21051639}}
{{ABSTRACT_PUBMED_21051639}}
==About this Structure==
==About this Structure==
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3LPG is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LPG OCA].
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[[3lpg]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LPG OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:21051639</ref><references group="xtra"/>
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<ref group="xtra">PMID:021051639</ref><references group="xtra"/><references/>
[[Category: Beta-glucuronidase]]
[[Category: Beta-glucuronidase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Sugar-binding domain]]
[[Category: Sugar-binding domain]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Nov 18 00:49:41 2010''
 

Revision as of 23:34, 10 April 2013

Template:STRUCTURE 3lpg

Structure of E. coli beta-Glucuronidase bound with a novel, potent inhibitor 3-(2-fluorophenyl)-1-(2-hydroxyethyl)-1-((6-methyl-2-oxo-1,2-dihydroquinolin-3-yl)methyl)urea

Template:ABSTRACT PUBMED 21051639

About this Structure

3lpg is a 2 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

  • Wallace BD, Wang H, Lane KT, Scott JE, Orans J, Koo JS, Venkatesh M, Jobin C, Yeh LA, Mani S, Redinbo MR. Alleviating cancer drug toxicity by inhibiting a bacterial enzyme. Science. 2010 Nov 5;330(6005):831-5. PMID:21051639 doi:10.1126/science.1191175

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