4i77
From Proteopedia
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{{STRUCTURE_4i77| PDB=4i77 | SCENE= }} | {{STRUCTURE_4i77| PDB=4i77 | SCENE= }} | ||
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===Lebrikizumab Fab bound to IL-13=== | ===Lebrikizumab Fab bound to IL-13=== | ||
| + | {{ABSTRACT_PUBMED_23357170}} | ||
| - | + | ==Disease== | |
| + | [[http://www.uniprot.org/uniprot/IL13_HUMAN IL13_HUMAN]] Defects in IL13 may be a cause of susceptibility to allergic rhinitis (ALRH) [MIM:[http://omim.org/entry/607154 607154]]. Allergic rhinitis is a common disease of complex inheritance and is characterized by mucosal inflammation caused by allergen exposure. | ||
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| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/IL13_HUMAN IL13_HUMAN]] Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses. | ||
==About this Structure== | ==About this Structure== | ||
Revision as of 19:16, 17 April 2013
Contents |
Lebrikizumab Fab bound to IL-13
Template:ABSTRACT PUBMED 23357170
Disease
[IL13_HUMAN] Defects in IL13 may be a cause of susceptibility to allergic rhinitis (ALRH) [MIM:607154]. Allergic rhinitis is a common disease of complex inheritance and is characterized by mucosal inflammation caused by allergen exposure.
Function
[IL13_HUMAN] Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses.
About this Structure
4i77 is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
