2wj8

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:2wj8.png|left|200px]]
 
- 
{{STRUCTURE_2wj8| PDB=2wj8 | SCENE= }}
{{STRUCTURE_2wj8| PDB=2wj8 | SCENE= }}
 +
===Respiratory Syncitial Virus RiboNucleoProtein===
 +
{{ABSTRACT_PUBMED_19965480}}
-
===RESPIRATORY SYNCITIAL VIRUS RIBONUCLEOPROTEIN===
+
==Function==
-
 
+
[[http://www.uniprot.org/uniprot/NCAP_HRSVA NCAP_HRSVA]] Encapsidates the genome, protecting it from nucleases. The nucleocapsid (NC) has a helical structure. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. During replication, encapsidation by protein N is coupled to RNA synthesis and all replicative products are resistant to nucleases.<ref>PMID:9299631</ref>
-
{{ABSTRACT_PUBMED_17567697}}
+
==About this Structure==
==About this Structure==
Line 14: Line 13:
==Reference==
==Reference==
-
<ref group="xtra">PMID:017567697</ref><ref group="xtra">PMID:019965480</ref><references group="xtra"/>
+
<ref group="xtra">PMID:019965480</ref><ref group="xtra">PMID:017567697</ref><references group="xtra"/><references/>
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
[[Category: Human respiratory syncytial virus a strain long]]
[[Category: Human respiratory syncytial virus a strain long]]
Line 24: Line 23:
[[Category: Duquerroy, S.]]
[[Category: Duquerroy, S.]]
[[Category: Eleouet, J.]]
[[Category: Eleouet, J.]]
-
[[Category: Maclellan, K.]]
+
[[Category: MacLellan, K.]]
[[Category: Rey, F A.]]
[[Category: Rey, F A.]]
[[Category: Tawar, R G.]]
[[Category: Tawar, R G.]]

Revision as of 19:24, 17 April 2013

Template:STRUCTURE 2wj8

Contents

Respiratory Syncitial Virus RiboNucleoProtein

Template:ABSTRACT PUBMED 19965480

Function

[NCAP_HRSVA] Encapsidates the genome, protecting it from nucleases. The nucleocapsid (NC) has a helical structure. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. During replication, encapsidation by protein N is coupled to RNA synthesis and all replicative products are resistant to nucleases.[1]

About this Structure

2wj8 is a 40 chain structure with sequence from Escherichia coli and Human respiratory syncytial virus a strain long. Full crystallographic information is available from OCA.

See Also

Reference

  • Tawar RG, Duquerroy S, Vonrhein C, Varela PF, Damier-Piolle L, Castagne N, MacLellan K, Bedouelle H, Bricogne G, Bhella D, Eleouet JF, Rey FA. Crystal structure of a nucleocapsid-like nucleoprotein-RNA complex of respiratory syncytial virus. Science. 2009 Nov 27;326(5957):1279-83. PMID:19965480 doi:326/5957/1279
  • Maclellan K, Loney C, Yeo RP, Bhella D. The 24-angstrom structure of respiratory syncytial virus nucleocapsid protein-RNA decameric rings. J Virol. 2007 Sep;81(17):9519-24. Epub 2007 Jun 13. PMID:17567697 doi:10.1128/JVI.00526-07
  1. ↑ Fearns R, Peeples ME, Collins PL. Increased expression of the N protein of respiratory syncytial virus stimulates minigenome replication but does not alter the balance between the synthesis of mRNA and antigenome. Virology. 1997 Sep 15;236(1):188-201. PMID:9299631 doi:10.1006/viro.1997.8734

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2wj8"
Personal tools