4iqy

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[[Image:4iqy.jpg|left|200px]]
 
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{{STRUCTURE_4iqy| PDB=4iqy | SCENE= }}
{{STRUCTURE_4iqy| PDB=4iqy | SCENE= }}
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===Crystal structure of the human protein-proximal ADP-ribosyl-hydrolase MacroD2===
===Crystal structure of the human protein-proximal ADP-ribosyl-hydrolase MacroD2===
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{{ABSTRACT_PUBMED_23474712}}
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==Function==
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[[http://www.uniprot.org/uniprot/MACD2_HUMAN MACD2_HUMAN]] Deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins.<ref>PMID:21257746</ref>
==About this Structure==
==About this Structure==
[[4iqy]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IQY OCA].
[[4iqy]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IQY OCA].
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==Reference==
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<references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Golia, B.]]
[[Category: Golia, B.]]

Revision as of 19:27, 17 April 2013

Template:STRUCTURE 4iqy

Contents

Crystal structure of the human protein-proximal ADP-ribosyl-hydrolase MacroD2

Template:ABSTRACT PUBMED 23474712

Function

[MACD2_HUMAN] Deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysine residues in histones and other proteins.[1]

About this Structure

4iqy is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Chen D, Vollmar M, Rossi MN, Phillips C, Kraehenbuehl R, Slade D, Mehrotra PV, von Delft F, Crosthwaite SK, Gileadi O, Denu JM, Ahel I. Identification of macrodomain proteins as novel O-acetyl-ADP-ribose deacetylases. J Biol Chem. 2011 Apr 15;286(15):13261-71. Epub 2011 Jan 21. PMID:21257746 doi:10.1074/jbc.M110.206771

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