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4eq1

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'''Unreleased structure'''
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{{STRUCTURE_4eq1| PDB=4eq1 | SCENE= }}
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===Crystal Structure of the ARNT PAS-B homodimer===
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{{ABSTRACT_PUBMED_23240775}}
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The entry 4eq1 is ON HOLD
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==Function==
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[[http://www.uniprot.org/uniprot/ARNT_HUMAN ARNT_HUMAN]] Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia.
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Authors: Gardner, K.H., Key, J.M.
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==About this Structure==
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[[4eq1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EQ1 OCA].
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Description: Crystal Structure of the ARNT PAS-B homodimer
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[[Category: Homo sapiens]]
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[[Category: Gardner, K H.]]
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[[Category: Key, J M.]]
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[[Category: Ahr]]
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[[Category: Dna-binding]]
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[[Category: Hif1]]
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[[Category: Hif2]]
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[[Category: Homodimer]]
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[[Category: Per-arnt-sim]]
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[[Category: Transcription]]
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[[Category: Transcription factor]]
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[[Category: Transcription regulation]]

Revision as of 20:22, 17 April 2013

Template:STRUCTURE 4eq1

Crystal Structure of the ARNT PAS-B homodimer

Template:ABSTRACT PUBMED 23240775

Function

[ARNT_HUMAN] Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia.

About this Structure

4eq1 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Proteopedia Page Contributors and Editors (what is this?)

OCA

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