4bhb
From Proteopedia
(Difference between revisions)
(New page: {{STRUCTURE_4bhb| PDB=4bhb | SCENE= }} ===Crystal structure of Mycobacterium tuberculosis O6-METHYLGUANINE METHYLTRANSFERASE=== {{ABSTRACT_PUBMED_23564173}} ==Function== [[http://www...) |
m (Protected "4bhb" [edit=sysop:move=sysop]) |
Revision as of 20:23, 17 April 2013
Crystal structure of Mycobacterium tuberculosis O6-METHYLGUANINE METHYLTRANSFERASE
Template:ABSTRACT PUBMED 23564173
Function
[OGT_MYCTU] Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated (By similarity).
About this Structure
4bhb is a 1 chain structure with sequence from Mycobacterium tuberculosis h37rv. Full crystallographic information is available from OCA.
