4ezr

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'''Unreleased structure'''
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{{STRUCTURE_4ezr| PDB=4ezr | SCENE= }}
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===Crystal structure of the substrate binding domain of E.coli DnaK in complex with the C-terminal part of drosocin (residues 12 to 19)===
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{{ABSTRACT_PUBMED_23562829}}
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The entry 4ezr is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/DNAK_ECOLI DNAK_ECOLI]] Plays an essential role in the initiation of phage lambda DNA replication, where it acts in an ATP-dependent fashion with the DnaJ protein to release lambda O and P proteins from the preprimosomal complex. DnaK is also involved in chromosomal DNA replication, possibly through an analogous interaction with the DnaA protein. Also participates actively in the response to hyperosmotic shock.[HAMAP-Rule:MF_00332] [[http://www.uniprot.org/uniprot/DROS_DROME DROS_DROME]] Antibacterial peptide with strong anti-Gram-negative bacteria activity.
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Authors: Zahn, M., Straeter, N.
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==About this Structure==
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[[4ezr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EZR OCA].
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Description: Crystal structure of the substrate binding domain of E.coli DnaK in complex with the C-terminal part of drosocin (residues 12 to 19)
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[[Category: Escherichia coli k-12]]
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[[Category: Straeter, N.]]
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[[Category: Zahn, M.]]
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[[Category: Chaperone]]
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[[Category: Chaperone-peptide binding protein complex]]
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[[Category: Peptide binding]]

Revision as of 20:25, 17 April 2013

Template:STRUCTURE 4ezr

Crystal structure of the substrate binding domain of E.coli DnaK in complex with the C-terminal part of drosocin (residues 12 to 19)

Template:ABSTRACT PUBMED 23562829

Function

[DNAK_ECOLI] Plays an essential role in the initiation of phage lambda DNA replication, where it acts in an ATP-dependent fashion with the DnaJ protein to release lambda O and P proteins from the preprimosomal complex. DnaK is also involved in chromosomal DNA replication, possibly through an analogous interaction with the DnaA protein. Also participates actively in the response to hyperosmotic shock.[HAMAP-Rule:MF_00332] [DROS_DROME] Antibacterial peptide with strong anti-Gram-negative bacteria activity.

About this Structure

4ezr is a 2 chain structure with sequence from Escherichia coli k-12. Full crystallographic information is available from OCA.

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OCA

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