4f00

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'''Unreleased structure'''
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{{STRUCTURE_4f00| PDB=4f00 | SCENE= }}
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===Crystal structure of the substrate binding domain of E.coli DnaK in complex with an apidaecin fragment from the bumblebee (residues 3 to 11)===
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{{ABSTRACT_PUBMED_23562829}}
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The entry 4f00 is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/DNAK_ECOLI DNAK_ECOLI]] Plays an essential role in the initiation of phage lambda DNA replication, where it acts in an ATP-dependent fashion with the DnaJ protein to release lambda O and P proteins from the preprimosomal complex. DnaK is also involved in chromosomal DNA replication, possibly through an analogous interaction with the DnaA protein. Also participates actively in the response to hyperosmotic shock.[HAMAP-Rule:MF_00332] [[http://www.uniprot.org/uniprot/APID_BOMPA APID_BOMPA]] Antibacterial peptide active against Gram-negative bacteria.
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Authors: Zahn, M., Straeter, N.
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==About this Structure==
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[[4f00]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F00 OCA].
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Description: Crystal structure of the substrate binding domain of E.coli DnaK in complex with an apidaecin fragment from the bumblebee (residues 3 to 11)
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[[Category: Escherichia coli k-12]]
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[[Category: Straeter, N.]]
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[[Category: Zahn, M.]]
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[[Category: Chaperone]]
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[[Category: Chaperone-immune system complex]]
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[[Category: Peptide binding mode]]

Revision as of 20:25, 17 April 2013

Template:STRUCTURE 4f00

Crystal structure of the substrate binding domain of E.coli DnaK in complex with an apidaecin fragment from the bumblebee (residues 3 to 11)

Template:ABSTRACT PUBMED 23562829

Function

[DNAK_ECOLI] Plays an essential role in the initiation of phage lambda DNA replication, where it acts in an ATP-dependent fashion with the DnaJ protein to release lambda O and P proteins from the preprimosomal complex. DnaK is also involved in chromosomal DNA replication, possibly through an analogous interaction with the DnaA protein. Also participates actively in the response to hyperosmotic shock.[HAMAP-Rule:MF_00332] [APID_BOMPA] Antibacterial peptide active against Gram-negative bacteria.

About this Structure

4f00 is a 2 chain structure with sequence from Escherichia coli k-12. Full crystallographic information is available from OCA.

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