3n5c

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "3n5c" [edit=sysop:move=sysop])
Line 1: Line 1:
-
[[Image:3n5c.png|left|200px]]
 
- 
-
<!--
 
-
The line below this paragraph, containing "STRUCTURE_3n5c", creates the "Structure Box" on the page.
 
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
 
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
 
-
or leave the SCENE parameter empty for the default display.
 
-
-->
 
{{STRUCTURE_3n5c| PDB=3n5c | SCENE= }}
{{STRUCTURE_3n5c| PDB=3n5c | SCENE= }}
- 
===Crystal Structure of Arf6DELTA13 complexed with GDP===
===Crystal Structure of Arf6DELTA13 complexed with GDP===
 +
{{ABSTRACT_PUBMED_20709080}}
-
 
+
==Function==
-
<!--
+
[[http://www.uniprot.org/uniprot/ARF6_HUMAN ARF6_HUMAN]] GTP-binding protein involved in protein trafficking; regulates endocytic recycling and cytoskeleton remodeling. May modulate vesicle budding and uncoating within the Golgi apparatus. Functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in the regulation of dendritic spine development (By similarity). Contributes to the regulation of dendritic branching and filopodia extension.<ref>PMID:7589240</ref> <ref>PMID:14978216</ref> <ref>PMID:11266366</ref>
-
The line below this paragraph, {{ABSTRACT_PUBMED_20709080}}, adds the Publication Abstract to the page
+
-
(as it appears on PubMed at http://www.pubmed.gov), where 20709080 is the PubMed ID number.
+
-
-->
+
-
{{ABSTRACT_PUBMED_20709080}}
+
==About this Structure==
==About this Structure==
Line 22: Line 10:
==Reference==
==Reference==
-
<ref group="xtra">PMID:20709080</ref><references group="xtra"/>
+
<ref group="xtra">PMID:020709080</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Aizel, K.]]
[[Category: Aizel, K.]]
[[Category: Biou, V.]]
[[Category: Biou, V.]]
[[Category: Cherfils, J.]]
[[Category: Cherfils, J.]]
 +
[[Category: Adp-ribosylation factor 6]]
 +
[[Category: Arf]]
 +
[[Category: Endocytosis]]
 +
[[Category: Protein transport]]
 +
[[Category: Small g protein]]
 +
[[Category: Small gtp-binding protein]]
 +
[[Category: Traffic]]
 +
[[Category: Unfolded protein]]

Revision as of 20:48, 17 April 2013

Template:STRUCTURE 3n5c

Contents

Crystal Structure of Arf6DELTA13 complexed with GDP

Template:ABSTRACT PUBMED 20709080

Function

[ARF6_HUMAN] GTP-binding protein involved in protein trafficking; regulates endocytic recycling and cytoskeleton remodeling. May modulate vesicle budding and uncoating within the Golgi apparatus. Functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in the regulation of dendritic spine development (By similarity). Contributes to the regulation of dendritic branching and filopodia extension.[1] [2] [3]

About this Structure

3n5c is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Biou V, Aizel K, Roblin P, Thureau A, Jacquet E, Hansson S, Guibert B, Guittet E, van Heijenoort C, Zeghouf M, Perez J, Cherfils J. SAXS and X-ray crystallography suggest an unfolding model for the GDP/GTP conformational switch of the small GTPase Arf6. J Mol Biol. 2010 Oct 1;402(4):696-707. Epub 2010 Aug 13. PMID:20709080 doi:10.1016/j.jmb.2010.08.002
  1. ↑ D'Souza-Schorey C, Stahl PD. Myristoylation is required for the intracellular localization and endocytic function of ARF6. Exp Cell Res. 1995 Nov;221(1):153-9. PMID:7589240 doi:http://dx.doi.org/10.1006/excr.1995.1362
  2. ↑ Gauthier-Campbell C, Bredt DS, Murphy TH, El-Husseini Ael-D. Regulation of dendritic branching and filopodia formation in hippocampal neurons by specific acylated protein motifs. Mol Biol Cell. 2004 May;15(5):2205-17. Epub 2004 Feb 20. PMID:14978216 doi:10.1091/mbc.E03-07-0493
  3. ↑ Pasqualato S, Menetrey J, Franco M, Cherfils J. The structural GDP/GTP cycle of human Arf6. EMBO Rep. 2001 Mar;2(3):234-8. PMID:11266366 doi:10.1093/embo-reports/kve043

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3n5c"
Personal tools