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3nau

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{{STRUCTURE_3nau| PDB=3nau | SCENE= }}
{{STRUCTURE_3nau| PDB=3nau | SCENE= }}
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===Crystal structure of ZHX2 HD2 (zinc-fingers and homeoboxes protein 2, homeodomain 2)===
===Crystal structure of ZHX2 HD2 (zinc-fingers and homeoboxes protein 2, homeodomain 2)===
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{{ABSTRACT_PUBMED_20509910}}
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==Function==
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[[http://www.uniprot.org/uniprot/ZHX2_HUMAN ZHX2_HUMAN]] Acts as a transcriptional repressor. Represses the promoter activity of the CDC25C gene stimulated by NFYA.<ref>PMID:12741956</ref>
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{{ABSTRACT_PUBMED_20509910}}
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==About this Structure==
==About this Structure==
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3NAU is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NAU OCA].
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[[3nau]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NAU OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:20509910</ref><references group="xtra"/>
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<ref group="xtra">PMID:020509910</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Bird, L E.]]
[[Category: Bird, L E.]]
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[[Category: Transcription]]
[[Category: Transcription]]
[[Category: Zhx2]]
[[Category: Zhx2]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 7 08:43:15 2010''
 

Revision as of 20:50, 17 April 2013

Template:STRUCTURE 3nau

Contents

Crystal structure of ZHX2 HD2 (zinc-fingers and homeoboxes protein 2, homeodomain 2)

Template:ABSTRACT PUBMED 20509910

Function

[ZHX2_HUMAN] Acts as a transcriptional repressor. Represses the promoter activity of the CDC25C gene stimulated by NFYA.[1]

About this Structure

3nau is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Bird LE, Ren J, Nettleship JE, Folkers GE, Owens RJ, Stammers DK. Novel structural features in two ZHX homeodomains derived from a systematic study of single and multiple domains. BMC Struct Biol. 2010 May 28;10:13. PMID:20509910 doi:10.1186/1472-6807-10-13
  1. ↑ Kawata H, Yamada K, Shou Z, Mizutani T, Yazawa T, Yoshino M, Sekiguchi T, Kajitani T, Miyamoto K. Zinc-fingers and homeoboxes (ZHX) 2, a novel member of the ZHX family, functions as a transcriptional repressor. Biochem J. 2003 Aug 1;373(Pt 3):747-57. PMID:12741956 doi:10.1042/BJ20030171

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