3n7d
From Proteopedia
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{{STRUCTURE_3n7d| PDB=3n7d | SCENE= }} | {{STRUCTURE_3n7d| PDB=3n7d | SCENE= }} | ||
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===Crystal structure of CopK bound to Cu(I) and Cu(II)=== | ===Crystal structure of CopK bound to Cu(I) and Cu(II)=== | ||
| + | {{ABSTRACT_PUBMED_021936507}} | ||
| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/COPK_RALME COPK_RALME]] Involved in resistance to copper. Can bind up to 2 copper ions. Has higher affinity for Cu(+) than for Cu(2+).<ref>PMID:18533181</ref> | ||
==About this Structure== | ==About this Structure== | ||
[[3n7d]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cupriavidus_metallidurans Cupriavidus metallidurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N7D OCA]. | [[3n7d]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cupriavidus_metallidurans Cupriavidus metallidurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N7D OCA]. | ||
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| + | ==Reference== | ||
| + | <ref group="xtra">PMID:021936507</ref><references group="xtra"/><references/> | ||
[[Category: Cupriavidus metallidurans]] | [[Category: Cupriavidus metallidurans]] | ||
[[Category: Ash, M R.]] | [[Category: Ash, M R.]] | ||
[[Category: Maher, M J.]] | [[Category: Maher, M J.]] | ||
| + | [[Category: Copper resistance]] | ||
| + | [[Category: Metal binding protein]] | ||
| + | [[Category: Methionine rich]] | ||
Revision as of 20:56, 17 April 2013
Contents |
Crystal structure of CopK bound to Cu(I) and Cu(II)
Template:ABSTRACT PUBMED 021936507
Function
[COPK_RALME] Involved in resistance to copper. Can bind up to 2 copper ions. Has higher affinity for Cu(+) than for Cu(2+).[1]
About this Structure
3n7d is a 2 chain structure with sequence from Cupriavidus metallidurans. Full crystallographic information is available from OCA.
Reference
- Ash MR, Chong LX, Maher MJ, Hinds MG, Xiao Z, Wedd AG. Molecular basis of the cooperative binding of Cu(I) and Cu(II) to the CopK protein from Cupriavidus metallidurans CH34. Biochemistry. 2011 Nov 1;50(43):9237-47. Epub 2011 Oct 4. PMID:21936507 doi:10.1021/bi200841f
- ↑ Bersch B, Favier A, Schanda P, van Aelst S, Vallaeys T, Coves J, Mergeay M, Wattiez R. Molecular structure and metal-binding properties of the periplasmic CopK protein expressed in Cupriavidus metallidurans CH34 during copper challenge. J Mol Biol. 2008 Jul 4;380(2):386-403. Epub 2008 May 15. PMID:18533181 doi:10.1016/j.jmb.2008.05.017
