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3mof
From Proteopedia
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{{STRUCTURE_3mof| PDB=3mof | SCENE= }} | {{STRUCTURE_3mof| PDB=3mof | SCENE= }} | ||
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===The structure of rat cytosolic PEPCK mutant A467G in complex with oxalate and GTP=== | ===The structure of rat cytosolic PEPCK mutant A467G in complex with oxalate and GTP=== | ||
| + | {{ABSTRACT_PUBMED_20476774}} | ||
| - | + | ==Function== | |
| - | + | [[http://www.uniprot.org/uniprot/PCKGC_RAT PCKGC_RAT]] Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. | |
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==About this Structure== | ==About this Structure== | ||
[[3mof]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MOF OCA]. | [[3mof]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MOF OCA]. | ||
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| + | ==See Also== | ||
| + | *[[Phosphoenolpyruvate carboxykinase|Phosphoenolpyruvate carboxykinase]] | ||
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:020476774</ref><references group="xtra"/><references/> |
[[Category: Rattus norvegicus]] | [[Category: Rattus norvegicus]] | ||
[[Category: Holyoak, T.]] | [[Category: Holyoak, T.]] | ||
[[Category: Johnson, T A.]] | [[Category: Johnson, T A.]] | ||
| + | [[Category: Gluconeogenesis]] | ||
| + | [[Category: Kinase]] | ||
| + | [[Category: Lyase]] | ||
Revision as of 20:56, 17 April 2013
Contents |
The structure of rat cytosolic PEPCK mutant A467G in complex with oxalate and GTP
Template:ABSTRACT PUBMED 20476774
Function
[PCKGC_RAT] Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
About this Structure
3mof is a 2 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.
See Also
Reference
- Johnson TA, Holyoak T. Increasing the conformational entropy of the Omega-loop lid domain in PEPCK impairs catalysis and decreases catalytic fidelity. Biochemistry. 2010 May 17. PMID:20476774 doi:10.1021/bi100399e
