3mzs

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[[Image:3mzs.png|left|200px]]
 
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{{STRUCTURE_3mzs| PDB=3mzs | SCENE= }}
{{STRUCTURE_3mzs| PDB=3mzs | SCENE= }}
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===Crystal Structure of Cytochrome P450 CYP11A1 in complex with 22-hydroxy-cholesterol===
===Crystal Structure of Cytochrome P450 CYP11A1 in complex with 22-hydroxy-cholesterol===
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{{ABSTRACT_PUBMED_21159775}}
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==Function==
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[[http://www.uniprot.org/uniprot/CP11A_BOVIN CP11A_BOVIN]] Catalyzes the side-chain cleavage reaction of cholesterol to pregnenolone.
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The line below this paragraph, {{ABSTRACT_PUBMED_21159775}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 21159775 is the PubMed ID number.
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{{ABSTRACT_PUBMED_21159775}}
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==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:21159775</ref><references group="xtra"/>
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<ref group="xtra">PMID:021159775</ref><references group="xtra"/><references/>
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Annalora, A.]]
[[Category: Annalora, A.]]
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[[Category: Pikuleva, I.]]
[[Category: Pikuleva, I.]]
[[Category: Stout, C D.]]
[[Category: Stout, C D.]]
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[[Category: Cholesterol]]
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[[Category: Cholesterol 20-22-desmolase]]
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[[Category: Cyp11a1]]
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[[Category: Cytochrome p450]]
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[[Category: Heme]]
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[[Category: Monooxygenase]]
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[[Category: Oxidoreductase]]
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[[Category: Side chain cleavage enzyme]]
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[[Category: Steroid metabolism]]

Revision as of 20:58, 17 April 2013

Template:STRUCTURE 3mzs

Contents

Crystal Structure of Cytochrome P450 CYP11A1 in complex with 22-hydroxy-cholesterol

Template:ABSTRACT PUBMED 21159775

Function

[CP11A_BOVIN] Catalyzes the side-chain cleavage reaction of cholesterol to pregnenolone.

About this Structure

3mzs is a 4 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

  • Mast N, Annalora AJ, Lodowski DT, Palczewski K, Stout CD, Pikuleva IA. Structural basis for three-step sequential catalysis by the cholesterol side chain cleavage enzyme CYP11A1. J Biol Chem. 2010 Dec 15. PMID:21159775 doi:10.1074/jbc.M110.188433

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