3mla

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[[Image:3mla.jpg|left|200px]]
 
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{{STRUCTURE_3mla| PDB=3mla | SCENE= }}
{{STRUCTURE_3mla| PDB=3mla | SCENE= }}
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===BaNadD in complex with inhibitor 1_02===
===BaNadD in complex with inhibitor 1_02===
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{{ABSTRACT_PUBMED_020578699}}
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==Function==
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[[http://www.uniprot.org/uniprot/NADD_BACAC NADD_BACAC]] Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity).
==About this Structure==
==About this Structure==
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3MLA is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MLA OCA].
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[[3mla]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MLA OCA].
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==Reference==
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<ref group="xtra">PMID:020578699</ref><references group="xtra"/><references/>
[[Category: Bacillus anthracis]]
[[Category: Bacillus anthracis]]
[[Category: Nicotinate-nucleotide adenylyltransferase]]
[[Category: Nicotinate-nucleotide adenylyltransferase]]
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[[Category: Nmnat-inhibitor complex]]
[[Category: Nmnat-inhibitor complex]]
[[Category: Transferase]]
[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 28 12:39:04 2010''
 

Revision as of 21:06, 17 April 2013

Template:STRUCTURE 3mla

Contents

BaNadD in complex with inhibitor 1_02

Template:ABSTRACT PUBMED 020578699

Function

[NADD_BACAC] Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity).

About this Structure

3mla is a 2 chain structure with sequence from Bacillus anthracis. Full crystallographic information is available from OCA.

Reference

  • Huang N, Kolhatkar R, Eyobo Y, Sorci L, Rodionova I, Osterman AL, Mackerell AD, Zhang H. Complexes of bacterial nicotinate mononucleotide adenylyltransferase with inhibitors: implication for structure-based drug design and improvement. J Med Chem. 2010 Jul 22;53(14):5229-39. PMID:20578699 doi:10.1021/jm100377f

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