3mkq

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[[Image:3mkq.png|left|200px]]
 
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{{STRUCTURE_3mkq| PDB=3mkq | SCENE= }}
{{STRUCTURE_3mkq| PDB=3mkq | SCENE= }}
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===Crystal structure of yeast alpha/betaprime-COP subcomplex of the COPI vesicular coat===
===Crystal structure of yeast alpha/betaprime-COP subcomplex of the COPI vesicular coat===
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{{ABSTRACT_PUBMED_20579721}}
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==Function==
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[[http://www.uniprot.org/uniprot/COPA_YEAST COPA_YEAST]] The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.<ref>PMID:17101773</ref>
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{{ABSTRACT_PUBMED_20579721}}
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==About this Structure==
==About this Structure==
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3MKQ is a 6 chains structure with sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] and [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_yjm789 Saccharomyces cerevisiae yjm789]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MKQ OCA].
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[[3mkq]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MKQ OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:20579721</ref><references group="xtra"/>
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<ref group="xtra">PMID:020579721</ref><references group="xtra"/><references/>
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Saccharomyces cerevisiae yjm789]]
 
[[Category: Goldberg, J.]]
[[Category: Goldberg, J.]]
[[Category: Lee, C.]]
[[Category: Lee, C.]]
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[[Category: Beta-propeller]]
[[Category: Beta-propeller]]
[[Category: Transport protein]]
[[Category: Transport protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 21 09:56:13 2010''
 

Revision as of 21:08, 17 April 2013

Template:STRUCTURE 3mkq

Contents

Crystal structure of yeast alpha/betaprime-COP subcomplex of the COPI vesicular coat

Template:ABSTRACT PUBMED 20579721

Function

[COPA_YEAST] The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.[1]

About this Structure

3mkq is a 6 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

  • Lee C, Goldberg J. Structure of coatomer cage proteins and the relationship among COPI, COPII, and clathrin vesicle coats. Cell. 2010 Jul 9;142(1):123-32. Epub 2010 Jun 24. PMID:20579721 doi:10.1016/j.cell.2010.05.030
  1. Gabriely G, Kama R, Gerst JE. Involvement of specific COPI subunits in protein sorting from the late endosome to the vacuole in yeast. Mol Cell Biol. 2007 Jan;27(2):526-40. Epub 2006 Nov 13. PMID:17101773 doi:MCB.00577-06

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