4fxd

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[[Image:4fxd.jpg|left|200px]]
 
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{{STRUCTURE_4fxd| PDB=4fxd | SCENE= }}
{{STRUCTURE_4fxd| PDB=4fxd | SCENE= }}
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===Crystal structure of yeast DNA polymerase alpha bound to DNA/RNA===
===Crystal structure of yeast DNA polymerase alpha bound to DNA/RNA===
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==Function==
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[[http://www.uniprot.org/uniprot/DPOA_YEAST DPOA_YEAST]] Catalytic component of DNA polymerase alpha, which in complex with DNA primase (DNA polymerase alpha:primase) consitutes a replicative polymerase. POL1 has a role in promoting telomere replication during interaction with CDC13.<ref>PMID:10898792</ref>
==About this Structure==
==About this Structure==
[[4fxd]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FXD OCA].
[[4fxd]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_s288c Saccharomyces cerevisiae s288c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FXD OCA].
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==Reference==
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<references group="xtra"/><references/>
[[Category: DNA-directed DNA polymerase]]
[[Category: DNA-directed DNA polymerase]]
[[Category: Saccharomyces cerevisiae s288c]]
[[Category: Saccharomyces cerevisiae s288c]]

Revision as of 10:33, 24 April 2013

Template:STRUCTURE 4fxd

Contents

Crystal structure of yeast DNA polymerase alpha bound to DNA/RNA

Function

[DPOA_YEAST] Catalytic component of DNA polymerase alpha, which in complex with DNA primase (DNA polymerase alpha:primase) consitutes a replicative polymerase. POL1 has a role in promoting telomere replication during interaction with CDC13.[1]

About this Structure

4fxd is a 6 chain structure with sequence from Saccharomyces cerevisiae s288c. Full crystallographic information is available from OCA.

Reference

  1. Qi H, Zakian VA. The Saccharomyces telomere-binding protein Cdc13p interacts with both the catalytic subunit of DNA polymerase alpha and the telomerase-associated est1 protein. Genes Dev. 2000 Jul 15;14(14):1777-88. PMID:10898792

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