4fhb
From Proteopedia
(Difference between revisions)
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| - | + | {{STRUCTURE_4fhb| PDB=4fhb | SCENE= }} | |
| + | ===Enhancing DHFR catalysis by binding of an allosteric regulator nanobody (Nb179)=== | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/DYR_ECOLI DYR_ECOLI]] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | ||
| - | + | ==About this Structure== | |
| - | + | [[4fhb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12] and [http://en.wikipedia.org/wiki/Lama_glama Lama glama]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FHB OCA]. | |
| - | + | [[Category: Dihydrofolate reductase]] | |
| + | [[Category: Escherichia coli k-12]] | ||
| + | [[Category: Lama glama]] | ||
| + | [[Category: Oyen, D.]] | ||
| + | [[Category: Allosteric activator]] | ||
| + | [[Category: Dihydrofolate reductase]] | ||
| + | [[Category: Nanobody]] | ||
| + | [[Category: Oxidoreductase-protein binding complex]] | ||
| + | [[Category: Reductase]] | ||
Revision as of 11:28, 24 April 2013
Enhancing DHFR catalysis by binding of an allosteric regulator nanobody (Nb179)
Function
[DYR_ECOLI] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
About this Structure
4fhb is a 2 chain structure with sequence from Escherichia coli k-12 and Lama glama. Full crystallographic information is available from OCA.
