4is3
From Proteopedia
(Difference between revisions)
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| - | + | {{STRUCTURE_4is3| PDB=4is3 | SCENE= }} | |
| + | ===Crystal structure of a 3alpha-hydroxysteroid dehydrogenase (BaiA2) associated with secondary bile acid synthesis from Clostridium scindens VPI12708 in complex with a putative NAD(+)-OH- adduct at 2.0 A resolution=== | ||
| - | + | ==Function== | |
| + | [[http://www.uniprot.org/uniprot/BAIA2_EUBSP BAIA2_EUBSP]] 7-alpha-dehydroxylation of cholic acid and chenodeoxycholate, yielding deoxycholic acid and lithocholic acid, respectively. Highest affinity with taurochenodeoxycholic acid. | ||
| - | + | ==About this Structure== | |
| - | + | [[4is3]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Clostridium_scindens Clostridium scindens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IS3 OCA]. | |
| - | + | [[Category: Clostridium scindens]] | |
| + | [[Category: JCSG, Joint Center for Structural Genomics.]] | ||
| + | [[Category: Jcsg]] | ||
| + | [[Category: Joint center for structural genomic]] | ||
| + | [[Category: Oxidoreductase]] | ||
| + | [[Category: Protein structure initiative]] | ||
| + | [[Category: Psi-biology]] | ||
| + | [[Category: Structural genomic]] | ||
Revision as of 11:31, 24 April 2013
Crystal structure of a 3alpha-hydroxysteroid dehydrogenase (BaiA2) associated with secondary bile acid synthesis from Clostridium scindens VPI12708 in complex with a putative NAD(+)-OH- adduct at 2.0 A resolution
Function
[BAIA2_EUBSP] 7-alpha-dehydroxylation of cholic acid and chenodeoxycholate, yielding deoxycholic acid and lithocholic acid, respectively. Highest affinity with taurochenodeoxycholic acid.
About this Structure
4is3 is a 4 chain structure with sequence from Clostridium scindens. Full crystallographic information is available from OCA.
