3nft
From Proteopedia
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{{STRUCTURE_3nft| PDB=3nft | SCENE= }} | {{STRUCTURE_3nft| PDB=3nft | SCENE= }} | ||
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===Near-atomic resolution analysis of BipD- A component of the type-III secretion system of Burkholderia pseudomallei=== | ===Near-atomic resolution analysis of BipD- A component of the type-III secretion system of Burkholderia pseudomallei=== | ||
| + | {{ABSTRACT_PUBMED_20823511}} | ||
| - | + | ==Function== | |
| - | + | [[http://www.uniprot.org/uniprot/BIPD_BURPS BIPD_BURPS]] Required for invasion of epithelial cells, as well as for survival within host cells, escape from endocytic vesicles and subsequent actin-tail formation. Probably regulates the secretion of effectors BipB and BipC and their final integration into the target cell membrane.<ref>PMID:12410823</ref> <ref>PMID:15289563</ref> | |
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==About this Structure== | ==About this Structure== | ||
| - | + | [[3nft]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Burkholderia_pseudomallei Burkholderia pseudomallei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NFT OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:020823511</ref><references group="xtra"/><references/> |
[[Category: Burkholderia pseudomallei]] | [[Category: Burkholderia pseudomallei]] | ||
[[Category: Cooper, J B.]] | [[Category: Cooper, J B.]] | ||
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[[Category: Transport protein]] | [[Category: Transport protein]] | ||
[[Category: Virulence]] | [[Category: Virulence]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 22 14:20:10 2010'' | ||
Revision as of 11:43, 24 April 2013
Contents |
Near-atomic resolution analysis of BipD- A component of the type-III secretion system of Burkholderia pseudomallei
Template:ABSTRACT PUBMED 20823511
Function
[BIPD_BURPS] Required for invasion of epithelial cells, as well as for survival within host cells, escape from endocytic vesicles and subsequent actin-tail formation. Probably regulates the secretion of effectors BipB and BipC and their final integration into the target cell membrane.[1] [2]
About this Structure
3nft is a 1 chain structure with sequence from Burkholderia pseudomallei. Full crystallographic information is available from OCA.
Reference
- Pal M, Erskine PT, Gill RS, Wood SP, Cooper JB. Near-atomic resolution analysis of BipD, a component of the type III secretion system of Burkholderia pseudomallei. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Sep 1;66(Pt, 9):990-3. Epub 2010 Aug 21. PMID:20823511 doi:10.1107/S1744309110026333
- ↑ Stevens MP, Wood MW, Taylor LA, Monaghan P, Hawes P, Jones PW, Wallis TS, Galyov EE. An Inv/Mxi-Spa-like type III protein secretion system in Burkholderia pseudomallei modulates intracellular behaviour of the pathogen. Mol Microbiol. 2002 Nov;46(3):649-59. PMID:12410823
- ↑ Stevens MP, Haque A, Atkins T, Hill J, Wood MW, Easton A, Nelson M, Underwood-Fowler C, Titball RW, Bancroft GJ, Galyov EE. Attenuated virulence and protective efficacy of a Burkholderia pseudomallei bsa type III secretion mutant in murine models of melioidosis. Microbiology. 2004 Aug;150(Pt 8):2669-76. PMID:15289563 doi:10.1099/mic.0.27146-0
