This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3nft
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | {{Seed}} | ||
| - | [[Image:3nft.png|left|200px]] | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_3nft", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_3nft| PDB=3nft | SCENE= }} | {{STRUCTURE_3nft| PDB=3nft | SCENE= }} | ||
| - | |||
===Near-atomic resolution analysis of BipD- A component of the type-III secretion system of Burkholderia pseudomallei=== | ===Near-atomic resolution analysis of BipD- A component of the type-III secretion system of Burkholderia pseudomallei=== | ||
| + | {{ABSTRACT_PUBMED_20823511}} | ||
| - | + | ==Function== | |
| - | + | [[http://www.uniprot.org/uniprot/BIPD_BURPS BIPD_BURPS]] Required for invasion of epithelial cells, as well as for survival within host cells, escape from endocytic vesicles and subsequent actin-tail formation. Probably regulates the secretion of effectors BipB and BipC and their final integration into the target cell membrane.<ref>PMID:12410823</ref> <ref>PMID:15289563</ref> | |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3nft]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Burkholderia_pseudomallei Burkholderia pseudomallei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NFT OCA]. | |
==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:020823511</ref><references group="xtra"/><references/> |
[[Category: Burkholderia pseudomallei]] | [[Category: Burkholderia pseudomallei]] | ||
[[Category: Cooper, J B.]] | [[Category: Cooper, J B.]] | ||
| Line 33: | Line 20: | ||
[[Category: Transport protein]] | [[Category: Transport protein]] | ||
[[Category: Virulence]] | [[Category: Virulence]] | ||
| - | |||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 22 14:20:10 2010'' | ||
Revision as of 11:43, 24 April 2013
Contents |
Near-atomic resolution analysis of BipD- A component of the type-III secretion system of Burkholderia pseudomallei
Template:ABSTRACT PUBMED 20823511
Function
[BIPD_BURPS] Required for invasion of epithelial cells, as well as for survival within host cells, escape from endocytic vesicles and subsequent actin-tail formation. Probably regulates the secretion of effectors BipB and BipC and their final integration into the target cell membrane.[1] [2]
About this Structure
3nft is a 1 chain structure with sequence from Burkholderia pseudomallei. Full crystallographic information is available from OCA.
Reference
- Pal M, Erskine PT, Gill RS, Wood SP, Cooper JB. Near-atomic resolution analysis of BipD, a component of the type III secretion system of Burkholderia pseudomallei. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Sep 1;66(Pt, 9):990-3. Epub 2010 Aug 21. PMID:20823511 doi:10.1107/S1744309110026333
- ↑ Stevens MP, Wood MW, Taylor LA, Monaghan P, Hawes P, Jones PW, Wallis TS, Galyov EE. An Inv/Mxi-Spa-like type III protein secretion system in Burkholderia pseudomallei modulates intracellular behaviour of the pathogen. Mol Microbiol. 2002 Nov;46(3):649-59. PMID:12410823
- ↑ Stevens MP, Haque A, Atkins T, Hill J, Wood MW, Easton A, Nelson M, Underwood-Fowler C, Titball RW, Bancroft GJ, Galyov EE. Attenuated virulence and protective efficacy of a Burkholderia pseudomallei bsa type III secretion mutant in murine models of melioidosis. Microbiology. 2004 Aug;150(Pt 8):2669-76. PMID:15289563 doi:10.1099/mic.0.27146-0
