3nkw
From Proteopedia
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m (Protected "3nkw" [edit=sysop:move=sysop]) |
Revision as of 11:47, 24 April 2013
Crystal structure of the complex of peptidoglycan recognition protein (PGRP-S) with N-acetyl glucosamine(NAG) at 2.6 A resolution
Function
[PGRP1_CAMDR] Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria. Involved in innate immunity. Is microbicidal for Gram-positive and Gram-negative bacteria and yeast. May function in intracellular killing of bacteria (By similarity).
About this Structure
3nkw is a 4 chain structure with sequence from Camelus dromedarius. This structure supersedes the now removed PDB entry 3c93. Full crystallographic information is available from OCA.
