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3npz

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[[Image:3npz.png|left|200px]]
 
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{{STRUCTURE_3npz| PDB=3npz | SCENE= }}
{{STRUCTURE_3npz| PDB=3npz | SCENE= }}
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===Prolactin Receptor (PRLR) Complexed with the Natural Hormone (PRL)===
===Prolactin Receptor (PRLR) Complexed with the Natural Hormone (PRL)===
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{{ABSTRACT_PUBMED_20875426}}
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==Function==
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[[http://www.uniprot.org/uniprot/PRL_HUMAN PRL_HUMAN]] Prolactin acts primarily on the mammary gland by promoting lactation. [[http://www.uniprot.org/uniprot/PRLR_RAT PRLR_RAT]] This is a receptor for the anterior pituitary hormone prolactin.
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{{ABSTRACT_PUBMED_20875426}}
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==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:20875426</ref><references group="xtra"/>
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<ref group="xtra">PMID:020875426</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: England, P.]]
[[Category: England, P.]]
[[Category: Goffin, V.]]
[[Category: Goffin, V.]]
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[[Category: Hormone]]
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[[Category: Hormone-hormone receptor complex]]
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[[Category: Hormone-receptor complex]]
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[[Category: Protein protein complex]]

Revision as of 11:53, 24 April 2013

Template:STRUCTURE 3npz

Contents

Prolactin Receptor (PRLR) Complexed with the Natural Hormone (PRL)

Template:ABSTRACT PUBMED 20875426

Function

[PRL_HUMAN] Prolactin acts primarily on the mammary gland by promoting lactation. [PRLR_RAT] This is a receptor for the anterior pituitary hormone prolactin.

About this Structure

3npz is a 3 chain structure with sequence from Homo sapiens and Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • van Agthoven J, Zhang C, Tallet E, Raynal B, Hoos S, Baron B, England P, Goffin V, Broutin I. Structural Characterization of the Stem-Stem Dimerization Interface between Prolactin Receptor Chains Complexed with the Natural Hormone. J Mol Biol. 2010 Sep 25. PMID:20875426 doi:10.1016/j.jmb.2010.09.036

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OCA

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