3npz
From Proteopedia
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{{STRUCTURE_3npz| PDB=3npz | SCENE= }} | {{STRUCTURE_3npz| PDB=3npz | SCENE= }} | ||
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===Prolactin Receptor (PRLR) Complexed with the Natural Hormone (PRL)=== | ===Prolactin Receptor (PRLR) Complexed with the Natural Hormone (PRL)=== | ||
+ | {{ABSTRACT_PUBMED_20875426}} | ||
- | + | ==Function== | |
- | + | [[http://www.uniprot.org/uniprot/PRL_HUMAN PRL_HUMAN]] Prolactin acts primarily on the mammary gland by promoting lactation. [[http://www.uniprot.org/uniprot/PRLR_RAT PRLR_RAT]] This is a receptor for the anterior pituitary hormone prolactin. | |
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==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:020875426</ref><references group="xtra"/><references/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Rattus norvegicus]] | [[Category: Rattus norvegicus]] | ||
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[[Category: England, P.]] | [[Category: England, P.]] | ||
[[Category: Goffin, V.]] | [[Category: Goffin, V.]] | ||
+ | [[Category: Hormone]] | ||
+ | [[Category: Hormone-hormone receptor complex]] | ||
+ | [[Category: Hormone-receptor complex]] | ||
+ | [[Category: Protein protein complex]] |
Revision as of 11:53, 24 April 2013
Contents |
Prolactin Receptor (PRLR) Complexed with the Natural Hormone (PRL)
Template:ABSTRACT PUBMED 20875426
Function
[PRL_HUMAN] Prolactin acts primarily on the mammary gland by promoting lactation. [PRLR_RAT] This is a receptor for the anterior pituitary hormone prolactin.
About this Structure
3npz is a 3 chain structure with sequence from Homo sapiens and Rattus norvegicus. Full crystallographic information is available from OCA.
Reference
- van Agthoven J, Zhang C, Tallet E, Raynal B, Hoos S, Baron B, England P, Goffin V, Broutin I. Structural Characterization of the Stem-Stem Dimerization Interface between Prolactin Receptor Chains Complexed with the Natural Hormone. J Mol Biol. 2010 Sep 25. PMID:20875426 doi:10.1016/j.jmb.2010.09.036