2f8i
From Proteopedia
(New page: 200px<br /> <applet load="2f8i" size="450" color="white" frame="true" align="right" spinBox="true" caption="2f8i, resolution 1.541Å" /> '''Human transthyreti...) |
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| - | [[Image:2f8i.gif|left|200px]]<br /> | + | [[Image:2f8i.gif|left|200px]]<br /><applet load="2f8i" size="350" color="white" frame="true" align="right" spinBox="true" |
| - | <applet load="2f8i" size=" | + | |
caption="2f8i, resolution 1.541Å" /> | caption="2f8i, resolution 1.541Å" /> | ||
'''Human transthyretin (TTR) complexed with Benzoxazole'''<br /> | '''Human transthyretin (TTR) complexed with Benzoxazole'''<br /> | ||
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==About this Structure== | ==About this Structure== | ||
| - | 2F8I is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with 205 as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http:// | + | 2F8I is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=205:'>205</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F8I OCA]. |
==Reference== | ==Reference== | ||
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[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
| - | [[Category: Kelly, J | + | [[Category: Kelly, J W.]] |
| - | [[Category: Mohamedmohaideen, N | + | [[Category: Mohamedmohaideen, N N.]] |
| - | [[Category: Palaninathan, S | + | [[Category: Palaninathan, S K.]] |
| - | [[Category: Sacchettini, J | + | [[Category: Sacchettini, J C]] |
[[Category: 205]] | [[Category: 205]] | ||
[[Category: ttr; amyloid; transthyretin]] | [[Category: ttr; amyloid; transthyretin]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:18:51 2008'' |
Revision as of 15:18, 21 February 2008
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Human transthyretin (TTR) complexed with Benzoxazole
Disease
Known diseases associated with this structure: Amyloid neuropathy, familial, several allelic types OMIM:[176300], Amyloidosis, senile systemic OMIM:[176300], Carpal tunnel syndrome, familial OMIM:[176300], Dystransthyretinemic hyperthyroxinemia OMIM:[176300]
About this Structure
2F8I is a Single protein structure of sequence from Homo sapiens with as ligand. Full crystallographic information is available from OCA.
Reference
Benzoxazoles as transthyretin amyloid fibril inhibitors: synthesis, evaluation, and mechanism of action., Razavi H, Palaninathan SK, Powers ET, Wiseman RL, Purkey HE, Mohamedmohaideen NN, Deechongkit S, Chiang KP, Dendle MT, Sacchettini JC, Kelly JW, Angew Chem Int Ed Engl. 2003 Jun 23;42(24):2758-61. PMID:12820260
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