3o2d
From Proteopedia
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{{STRUCTURE_3o2d| PDB=3o2d | SCENE= }} | {{STRUCTURE_3o2d| PDB=3o2d | SCENE= }} | ||
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===Crystal structure of HIV-1 primary receptor CD4 in complex with a potent antiviral antibody=== | ===Crystal structure of HIV-1 primary receptor CD4 in complex with a potent antiviral antibody=== | ||
+ | {{ABSTRACT_PUBMED_21134642}} | ||
- | + | ==Function== | |
- | + | [[http://www.uniprot.org/uniprot/CD4_HUMAN CD4_HUMAN]] Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts. | |
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==About this Structure== | ==About this Structure== | ||
- | + | [[3o2d]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O2D OCA]. | |
==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:021134642</ref><references group="xtra"/><references/> |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
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[[Category: Monoclonal antibody]] | [[Category: Monoclonal antibody]] | ||
[[Category: T cell coreceptor]] | [[Category: T cell coreceptor]] | ||
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- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 22 09:55:18 2010'' |
Revision as of 12:02, 24 April 2013
Contents |
Crystal structure of HIV-1 primary receptor CD4 in complex with a potent antiviral antibody
Template:ABSTRACT PUBMED 21134642
Function
[CD4_HUMAN] Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts.
About this Structure
3o2d is a 3 chain structure with sequence from Homo sapiens and Mus musculus. Full crystallographic information is available from OCA.
Reference
- Freeman MM, Seaman MS, Rits-Volloch S, Hong X, Kao CY, Ho DD, Chen B. Crystal structure of HIV-1 primary receptor CD4 in complex with a potent antiviral antibody. Structure. 2010 Dec 8;18(12):1632-41. PMID:21134642 doi:10.1016/j.str.2010.09.017