3nfq

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[[Image:3nfq.png|left|200px]]
 
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{{STRUCTURE_3nfq| PDB=3nfq | SCENE= }}
{{STRUCTURE_3nfq| PDB=3nfq | SCENE= }}
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===Crystal structure of the conserved central domain of yeast Spn1/Iws1===
===Crystal structure of the conserved central domain of yeast Spn1/Iws1===
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{{ABSTRACT_PUBMED_20875428}}
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==Function==
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[[http://www.uniprot.org/uniprot/IWS1_YEAST IWS1_YEAST]] Transcription factor involved in RNA polymerase II transcription regulation. May function in both SPT15/TBP post-recruitment and recruitment steps of transcription.<ref>PMID:12524336</ref> <ref>PMID:12556496</ref>
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{{ABSTRACT_PUBMED_20875428}}
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==About this Structure==
==About this Structure==
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3NFQ is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NFQ OCA].
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[[3nfq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NFQ OCA].
==Reference==
==Reference==
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<ref group="xtra">PMID:20875428</ref><references group="xtra"/>
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<ref group="xtra">PMID:020875428</ref><references group="xtra"/><references/>
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Luger, K.]]
[[Category: Luger, K.]]
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[[Category: Spn1]]
[[Category: Spn1]]
[[Category: Transcription]]
[[Category: Transcription]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Nov 18 00:19:59 2010''
 

Revision as of 12:06, 24 April 2013

Template:STRUCTURE 3nfq

Contents

Crystal structure of the conserved central domain of yeast Spn1/Iws1

Template:ABSTRACT PUBMED 20875428

Function

[IWS1_YEAST] Transcription factor involved in RNA polymerase II transcription regulation. May function in both SPT15/TBP post-recruitment and recruitment steps of transcription.[1] [2]

About this Structure

3nfq is a 2 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

  • Pujari V, Radebaugh CA, Chodaparambil JV, Muthurajan UM, Almeida AR, Fischbeck JA, Luger K, Stargell LA. The Transcription Factor Spn1 Regulates Gene Expression via a Highly Conserved Novel Structural Motif. J Mol Biol. 2010 Sep 25. PMID:20875428 doi:10.1016/j.jmb.2010.09.040
  1. ↑ Fischbeck JA, Kraemer SM, Stargell LA. SPN1, a conserved gene identified by suppression of a postrecruitment-defective yeast TATA-binding protein mutant. Genetics. 2002 Dec;162(4):1605-16. PMID:12524336
  2. ↑ Lindstrom DL, Squazzo SL, Muster N, Burckin TA, Wachter KC, Emigh CA, McCleery JA, Yates JR 3rd, Hartzog GA. Dual roles for Spt5 in pre-mRNA processing and transcription elongation revealed by identification of Spt5-associated proteins. Mol Cell Biol. 2003 Feb;23(4):1368-78. PMID:12556496

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