3ngx

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[[Image:3ngx.jpg|left|200px]]
 
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{{STRUCTURE_3ngx| PDB=3ngx | SCENE= }}
{{STRUCTURE_3ngx| PDB=3ngx | SCENE= }}
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===Crystal structure of bifunctional 5,10-methylenetetrahydrofolate dehydrogenase / cyclohydrolase from Thermoplasma acidophilum===
===Crystal structure of bifunctional 5,10-methylenetetrahydrofolate dehydrogenase / cyclohydrolase from Thermoplasma acidophilum===
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{{ABSTRACT_PUBMED_21333632}}
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==Function==
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[[http://www.uniprot.org/uniprot/FOLD_THEAC FOLD_THEAC]] Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate (By similarity).
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{{ABSTRACT_PUBMED_21333632}}
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==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:21333632</ref><references group="xtra"/>
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<ref group="xtra">PMID:021333632</ref><references group="xtra"/><references/>
[[Category: Thermoplasma acidophilum]]
[[Category: Thermoplasma acidophilum]]
[[Category: Hwang, K W.]]
[[Category: Hwang, K W.]]
[[Category: Lee, W H.]]
[[Category: Lee, W H.]]
[[Category: Sung, M W.]]
[[Category: Sung, M W.]]
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[[Category: 10-methenyltetrahydrofolate]]
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[[Category: 10-methenyltetrahydrofolate to 10-formyltetrahydrofolate]]
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[[Category: 10-methylenetetrahydrofolate to 5]]
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[[Category: Catalyzes the oxidation of 5]]
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[[Category: Hydrolase]]
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[[Category: Methylenetetrahydrofolate dehydrogenase/cyclohydrolase]]
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[[Category: Oxidoreductase]]
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[[Category: The hydrolysis of 5]]

Revision as of 12:07, 24 April 2013

Template:STRUCTURE 3ngx

Contents

Crystal structure of bifunctional 5,10-methylenetetrahydrofolate dehydrogenase / cyclohydrolase from Thermoplasma acidophilum

Template:ABSTRACT PUBMED 21333632

Function

[FOLD_THEAC] Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate (By similarity).

About this Structure

3ngx is a 2 chain structure with sequence from Thermoplasma acidophilum. Full crystallographic information is available from OCA.

Reference

  • Lee WH, Sung MW, Kim JH, Kim YK, Han A, Hwang KY. Crystal structure of bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/cyclohydrolase from Thermoplasma acidophilum. Biochem Biophys Res Commun. 2011 Mar 18;406(3):459-63. Epub 2011 Feb 17. PMID:21333632 doi:10.1016/j.bbrc.2011.02.074

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