3ngx
From Proteopedia
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===Crystal structure of bifunctional 5,10-methylenetetrahydrofolate dehydrogenase / cyclohydrolase from Thermoplasma acidophilum=== | ===Crystal structure of bifunctional 5,10-methylenetetrahydrofolate dehydrogenase / cyclohydrolase from Thermoplasma acidophilum=== | ||
+ | {{ABSTRACT_PUBMED_21333632}} | ||
- | + | ==Function== | |
- | + | [[http://www.uniprot.org/uniprot/FOLD_THEAC FOLD_THEAC]] Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate (By similarity). | |
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==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
- | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:021333632</ref><references group="xtra"/><references/> |
[[Category: Thermoplasma acidophilum]] | [[Category: Thermoplasma acidophilum]] | ||
[[Category: Hwang, K W.]] | [[Category: Hwang, K W.]] | ||
[[Category: Lee, W H.]] | [[Category: Lee, W H.]] | ||
[[Category: Sung, M W.]] | [[Category: Sung, M W.]] | ||
+ | [[Category: 10-methenyltetrahydrofolate]] | ||
+ | [[Category: 10-methenyltetrahydrofolate to 10-formyltetrahydrofolate]] | ||
+ | [[Category: 10-methylenetetrahydrofolate to 5]] | ||
+ | [[Category: Catalyzes the oxidation of 5]] | ||
+ | [[Category: Hydrolase]] | ||
+ | [[Category: Methylenetetrahydrofolate dehydrogenase/cyclohydrolase]] | ||
+ | [[Category: Oxidoreductase]] | ||
+ | [[Category: The hydrolysis of 5]] |
Revision as of 12:07, 24 April 2013
Contents |
Crystal structure of bifunctional 5,10-methylenetetrahydrofolate dehydrogenase / cyclohydrolase from Thermoplasma acidophilum
Template:ABSTRACT PUBMED 21333632
Function
[FOLD_THEAC] Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate (By similarity).
About this Structure
3ngx is a 2 chain structure with sequence from Thermoplasma acidophilum. Full crystallographic information is available from OCA.
Reference
- Lee WH, Sung MW, Kim JH, Kim YK, Han A, Hwang KY. Crystal structure of bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/cyclohydrolase from Thermoplasma acidophilum. Biochem Biophys Res Commun. 2011 Mar 18;406(3):459-63. Epub 2011 Feb 17. PMID:21333632 doi:10.1016/j.bbrc.2011.02.074
Categories: Thermoplasma acidophilum | Hwang, K W. | Lee, W H. | Sung, M W. | 10-methenyltetrahydrofolate | 10-methenyltetrahydrofolate to 10-formyltetrahydrofolate | 10-methylenetetrahydrofolate to 5 | Catalyzes the oxidation of 5 | Hydrolase | Methylenetetrahydrofolate dehydrogenase/cyclohydrolase | Oxidoreductase | The hydrolysis of 5