Sandbox Reserved 691

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== Function ==
== Function ==
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Through the binding of two sodium ions, dopamine can then bind after which the protein undergoes a conformational change to allow for the sodium and dopamine to enter the cell. Similar to other ionic pumps, the flow of sodium is coupled with the flow of a chlorine ion, in order to balance the charge build up.
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Through the binding of two sodium ions, dopamine can then bind after which the protein undergoes a conformational change to allow for the sodium and dopamine to enter the cell. Similar to other ionic pumps, the flow of sodium is coupled with the flow of a chlorine ion, in order to balance the charge build up.<scene name='Sandbox_Reserved_691/2a65_ligand/1'>LIGAND SWAG</scene>

Revision as of 00:51, 25 April 2013

This Sandbox is Reserved from 30/01/2013, through 30/12/2013 for use in the course "Biochemistry II" taught by Hannah Tims at the Messiah College. This reservation includes Sandbox Reserved 686 through Sandbox Reserved 700.
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Dopamine Active Transporter

Dopamine Active Transporter (DAT) is a transmembrane protein found in human neurons, that is responsible for the reuptake of the neurotransmitter dopamine from the synapse back into synaptic vesicles for storage and later release. The action of this protein is responsible for the termination of signaling in dopaminergic pathways, which are responsible for many important biological functions such as cognition, motor control, sleep, and emotion.

LEUTAA, a bacterial homolog for human Na+/Cl- dependent neurotransmitter transporters such as DAT

Drag the structure with the mouse to rotate

Function

Through the binding of two sodium ions, dopamine can then bind after which the protein undergoes a conformational change to allow for the sodium and dopamine to enter the cell. Similar to other ionic pumps, the flow of sodium is coupled with the flow of a chlorine ion, in order to balance the charge build up.

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