Sandbox Reserved 687

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<Structure load='4I2P' size='500' frame='true' align='right' caption='Crystal structure of HIV-1 reverse transcriptase in complex with rilpivirine' scene='Insert optional scene name here' />
<Structure load='4I2P' size='500' frame='true' align='right' caption='Crystal structure of HIV-1 reverse transcriptase in complex with rilpivirine' scene='Insert optional scene name here' />
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<scene name='Sandbox_Reserved_687/Rvp_in_nnrbi_of_p66/1'>NNRTI binding pocket</scene> In red are the binding pocket residues p66 (Leu-100, Lys-101, Lys-103, Val-106, Thr-107, Val-108, Val-179, Tyr-181, Tyr-188, Val-189, Gly-190, Phe-227, Trp-229, Leu- 234, and Tyr-318) and p51(Glu-138). Singh et al.
Tenofovir
Tenofovir

Revision as of 02:21, 29 April 2013

This Sandbox is Reserved from 30/01/2013, through 30/12/2013 for use in the course "Biochemistry II" taught by Hannah Tims at the Messiah College. This reservation includes Sandbox Reserved 686 through Sandbox Reserved 700.
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  • Click the 3D button (when editing, above the wikitext box) to insert Jmol.
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Complera: Emtricitabine/rilpivirine/tenofovir

Rilpivirine

Crystal structure of HIV-1 reverse transcriptase in complex with rilpivirine

Drag the structure with the mouse to rotate

In red are the binding pocket residues p66 (Leu-100, Lys-101, Lys-103, Val-106, Thr-107, Val-108, Val-179, Tyr-181, Tyr-188, Val-189, Gly-190, Phe-227, Trp-229, Leu- 234, and Tyr-318) and p51(Glu-138). Singh et al.

Tenofovir Image:Tenofovir.png

HIV-1 reverse transcriptase crosslinked to tenofovir terminated template-primer

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Emtricitabine Image:Emtricitabine3.png

Insert caption here

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