User:Fadel A. Samatey/FlhBc I
From Proteopedia
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====''Salmonella''==== | ====''Salmonella''==== | ||
| - | FlhB from ''Salmonella typhimurium'' consists of 383 amino acids. The cytoplasmic domain 219-383 (length 165, 43% of full length) was crystallized. The resulting model [[3b0z]] includes coordinates for residues 229-353 (length 125, 76% of the crystallized length). The [[asymmetric unit]] contains a single molecule (<scene name='User:Fadel_A._Samatey/Workbench/I3DC-1/Flhb_st/6'>restore initial scene</scene>). As explained in the publication, the position of the long alpha helix appears to be stabilized by | + | FlhB from ''Salmonella typhimurium'' consists of 383 amino acids. The cytoplasmic domain 219-383 (length 165, 43% of full length) was crystallized. The resulting model [[3b0z]] includes coordinates for residues 229-353 (length 125, 76% of the crystallized length). The [[asymmetric unit]] contains a single molecule (<scene name='User:Fadel_A._Samatey/Workbench/I3DC-1/Flhb_st/6'>restore initial scene</scene>). |
| + | <center><span style="background-color:black;padding:4px;">{{Template:ColorKey_Helix}}, | ||
| + | {{Template:ColorKey_Strand}}</span></center> | ||
| + | As explained in the publication, the position of the long alpha helix appears to be stabilized by | ||
[[crystal contacts]] (not shown). | [[crystal contacts]] (not shown). | ||
<!--<scene name='User:Fadel_A._Samatey/Workbench/I3DC-1/Flhb_st_xtl_contacts/2'>crystal contacts</scene> (use the ''popup'' button to see details).--> | <!--<scene name='User:Fadel_A._Samatey/Workbench/I3DC-1/Flhb_st_xtl_contacts/2'>crystal contacts</scene> (use the ''popup'' button to see details).--> | ||
Revision as of 13:24, 29 April 2013
Interactive 3D Complement in Proteopedia
Inhibition of a type III secretion system by the deletion of a short loop in one of its membrane proteins.
Vladimir A. Meshcheryakov, Akio Kitao, Hideyuki Matsunami and Fadel A. Samatey. Acta Cryst. D69: 812-820 (2013). doi:10.1107/S0907444913002102
Brief Introduction
FlhB is a membrane protein that is part of the flagellum-specific secretion apparatus. It is required for secretion of flagellar proteins, and for bacterial motility. FlhB is paralogous to a protein in the virulence type III secretion system. FlhB has a hydrophobic integral membrane domain, predicted to have four transmembrane helices, a flexible linker that is highly conserved and essential for function, and a cytoplasmic domain. The present study reports the structures of the cytoplasmic domains of two bacterial taxa. (Please see the publication for a more detailed introduction.)
Molecular Tour: FlhBc Structures
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References and Notes
Notes for Developers
- Image:Workbench 3b0z.pdb.gz
- Image:Workbench 3b1s.pdb.gz
- Image:Workbench 3b0z 3b1sCD.pdb 1.1 is 3b0z(St) while 1.2 is 3b1s chains C and D. Not aligned.
- Image:Workbench 3b0z 3b1sCD aligned.pdb
