4h2d

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{{STRUCTURE_4h2d| PDB=4h2d | SCENE= }}
{{STRUCTURE_4h2d| PDB=4h2d | SCENE= }}
===Crystal structure of NDOR1===
===Crystal structure of NDOR1===
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{{ABSTRACT_PUBMED_11371558}}
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{{ABSTRACT_PUBMED_23596212}}
==Function==
==Function==

Revision as of 06:38, 2 May 2013

Template:STRUCTURE 4h2d

Contents

Crystal structure of NDOR1

Template:ABSTRACT PUBMED 23596212

Function

[NDOR1_HUMAN] Oxidoreductase that catalyzes the NADP-dependent reduction of cytochrome c and one-electron acceptors, such as doxorubicin, potassium ferricyanide and menadione (in vitro).[1]

About this Structure

4h2d is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Hubbard PA, Shen AL, Paschke R, Kasper CB, Kim JJ. NADPH-cytochrome P450 oxidoreductase. Structural basis for hydride and electron transfer. J Biol Chem. 2001 Aug 3;276(31):29163-70. Epub 2001 May 22. PMID:11371558 doi:http://dx.doi.org/10.1074/jbc.M101731200
  • Sibille N, Blackledge M, Brutscher B, Coves J, Bersch B. Solution structure of the sulfite reductase flavodoxin-like domain from Escherichia coli. Biochemistry. 2005 Jun 28;44(25):9086-95. PMID:15966732 doi:10.1021/bi050437p
  • Hamdane D, Xia C, Im SC, Zhang H, Kim JJ, Waskell L. Structure and function of an NADPH-cytochrome P450 oxidoreductase in an open conformation capable of reducing cytochrome P450. J Biol Chem. 2009 Apr 24;284(17):11374-84. Epub 2009 Jan 26. PMID:19171935 doi:10.1074/jbc.M807868200
  1. ↑ Paine MJ, Garner AP, Powell D, Sibbald J, Sales M, Pratt N, Smith T, Tew DG, Wolf CR. Cloning and characterization of a novel human dual flavin reductase. J Biol Chem. 2000 Jan 14;275(2):1471-8. PMID:10625700

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OCA

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