4iox

From Proteopedia

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'''Unreleased structure'''
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{{STRUCTURE_4iox| PDB=4iox | SCENE= }}
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===The structure of the herpes simplex virus DNA-packaging motor pUL15 C-terminal nuclease domain provides insights into cleavage of concatemeric viral genome precursors===
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{{ABSTRACT_PUBMED_23596306}}
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The entry 4iox is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/TRM3_HHV11 TRM3_HHV11]] Component of the molecular motor that translocates genomic DNA in empty capsid during DNA packaging. Heterodimerizes with small terminase protein to be docked on capsid portal protein. The latter forms a ring in which genomic DNA in translocated into the capsid. May have or induce an endonuclease activity to cleave the genome concatemer after encapsidation.
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Authors: Selvarajan Sigamani, S., Zhao, H., Kamau, Y., Tang, L.
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==About this Structure==
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[[4iox]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_herpesvirus_1 Human herpesvirus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IOX OCA].
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Description: The structure of the herpes simplex virus DNA-packaging motor pUL15 C-terminal nuclease domain provides insights into cleavage of concatemeric viral genome precursors
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[[Category: Human herpesvirus 1]]
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[[Category: Kamau, Y.]]
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[[Category: Sigamani, S Selvarajan.]]
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[[Category: Tang, L.]]
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[[Category: Zhao, H.]]
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[[Category: Nuclease]]
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[[Category: Viral protein]]

Revision as of 07:34, 2 May 2013

Template:STRUCTURE 4iox

The structure of the herpes simplex virus DNA-packaging motor pUL15 C-terminal nuclease domain provides insights into cleavage of concatemeric viral genome precursors

Template:ABSTRACT PUBMED 23596306

Function

[TRM3_HHV11] Component of the molecular motor that translocates genomic DNA in empty capsid during DNA packaging. Heterodimerizes with small terminase protein to be docked on capsid portal protein. The latter forms a ring in which genomic DNA in translocated into the capsid. May have or induce an endonuclease activity to cleave the genome concatemer after encapsidation.

About this Structure

4iox is a 4 chain structure with sequence from Human herpesvirus 1. Full crystallographic information is available from OCA.

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OCA

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