2lyh

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'''Unreleased structure'''
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{{STRUCTURE_2lyh| PDB=2lyh | SCENE= }}
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===Structure of Faap24 residues 141-215===
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The entry 2lyh is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/FAP24_HUMAN FAP24_HUMAN]] Plays a role in DNA repair through recruitment of the FA core complex to damaged DNA. Regulates FANCD2 monoubiquitination upon DNA damage. Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed. Targets FANCM/FAAP24 complex to the DNA, preferentially to single strand DNA.
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Authors: Wienk, H., Slootweg, J., Kaptein, R., Boelens, R., Folkers, G.E.
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==About this Structure==
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[[2lyh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LYH OCA].
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Description: Structure of Faap24 residues 141-215
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[[Category: Homo sapiens]]
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[[Category: Boelens, R.]]
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[[Category: Folkers, G E.]]
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[[Category: Kaptein, R.]]
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[[Category: Slootweg, J.]]
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[[Category: Wienk, H.]]
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[[Category: Dna binding protein]]
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[[Category: Fanconi anemia]]
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[[Category: Interstrand crosslink repair]]

Revision as of 07:43, 2 May 2013

Template:STRUCTURE 2lyh

Structure of Faap24 residues 141-215

Function

[FAP24_HUMAN] Plays a role in DNA repair through recruitment of the FA core complex to damaged DNA. Regulates FANCD2 monoubiquitination upon DNA damage. Induces chromosomal instability as well as hypersensitivity to DNA cross-linking agents, when repressed. Targets FANCM/FAAP24 complex to the DNA, preferentially to single strand DNA.

About this Structure

2lyh is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.

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OCA

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