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2fji
From Proteopedia
(New page: 200px<br /><applet load="2fji" size="450" color="white" frame="true" align="right" spinBox="true" caption="2fji, resolution 2.40Å" /> '''Crystal structure of...) |
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| - | [[Image:2fji.gif|left|200px]]<br /><applet load="2fji" size=" | + | [[Image:2fji.gif|left|200px]]<br /><applet load="2fji" size="350" color="white" frame="true" align="right" spinBox="true" |
caption="2fji, resolution 2.40Å" /> | caption="2fji, resolution 2.40Å" /> | ||
'''Crystal structure of the C-terminal domain of the exocyst subunit Sec6p'''<br /> | '''Crystal structure of the C-terminal domain of the exocyst subunit Sec6p'''<br /> | ||
==Overview== | ==Overview== | ||
| - | The exocyst is a conserved protein complex essential for trafficking | + | The exocyst is a conserved protein complex essential for trafficking secretory vesicles to the plasma membrane. The structure of the C-terminal domain of the exocyst subunit Sec6p reveals multiple helical bundles, which are structurally and topologically similar to Exo70p and the C-terminal domains of Exo84p and Sec15, despite <10% sequence identity. The helical bundles appear to be evolutionarily related molecular scaffolds that have diverged to create functionally distinct exocyst proteins. |
==About this Structure== | ==About this Structure== | ||
| - | 2FJI is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http:// | + | 2FJI is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FJI OCA]. |
==Reference== | ==Reference== | ||
| Line 14: | Line 14: | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
[[Category: Munson, M.]] | [[Category: Munson, M.]] | ||
| - | [[Category: Sivaram, M | + | [[Category: Sivaram, M V.]] |
[[Category: exocyst complex]] | [[Category: exocyst complex]] | ||
[[Category: exocytosis]] | [[Category: exocytosis]] | ||
[[Category: tandem helical bundles]] | [[Category: tandem helical bundles]] | ||
| - | ''Page seeded by [http:// | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:22:02 2008'' |
Revision as of 15:22, 21 February 2008
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Crystal structure of the C-terminal domain of the exocyst subunit Sec6p
Overview
The exocyst is a conserved protein complex essential for trafficking secretory vesicles to the plasma membrane. The structure of the C-terminal domain of the exocyst subunit Sec6p reveals multiple helical bundles, which are structurally and topologically similar to Exo70p and the C-terminal domains of Exo84p and Sec15, despite <10% sequence identity. The helical bundles appear to be evolutionarily related molecular scaffolds that have diverged to create functionally distinct exocyst proteins.
About this Structure
2FJI is a Single protein structure of sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.
Reference
The structure of the exocyst subunit Sec6p defines a conserved architecture with diverse roles., Sivaram MV, Furgason ML, Brewer DN, Munson M, Nat Struct Mol Biol. 2006 Jun;13(6):555-6. Epub 2006 May 14. PMID:16699513
Page seeded by OCA on Thu Feb 21 17:22:02 2008
