4f3c

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'''Unreleased structure'''
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{{STRUCTURE_4f3c| PDB=4f3c | SCENE= }}
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===Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Salmonella enterica with butyl-thio-DADMe-Immucillin-A===
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The entry 4f3c is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/E8NLP5_SALET E8NLP5_SALET]] Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity).[HAMAP-Rule:MF_01684]
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Authors: Haapalainen, A.M., Thomas, K., Bonanno, J.B., Almo, S.C., Schramm, V.L.
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==About this Structure==
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[[4f3c]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_choleraesuis_str._scsa50 Salmonella enterica subsp. enterica serovar choleraesuis str. scsa50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F3C OCA].
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Description: Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Salmonella enterica with butyl-thio-DADMe-Immucillin-A
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[[Category: Adenosylhomocysteine nucleosidase]]
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[[Category: Salmonella enterica subsp. enterica serovar choleraesuis str. scsa50]]
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[[Category: Almo, S C.]]
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[[Category: Bonanno, J B.]]
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[[Category: Haapalainen, A M.]]
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[[Category: Schramm, V L.]]
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[[Category: Thomas, K.]]
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[[Category: 5'-methylthioadenosine/s-adenosylhomocysteine nucleosidase]]
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[[Category: Acting on glycosyl bond]]
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[[Category: Adenosylhomocysteine nucleosidase activity]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: L-methionine biosynthetic process from s-adenosylmethionine]]
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[[Category: L-methionine salvage from methylthioadenosine]]
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[[Category: Methylthioadenosine nucleosidase activity]]

Revision as of 07:49, 2 May 2013

Template:STRUCTURE 4f3c

Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Salmonella enterica with butyl-thio-DADMe-Immucillin-A

Function

[E8NLP5_SALET] Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity).[HAMAP-Rule:MF_01684]

About this Structure

4f3c is a 2 chain structure with sequence from Salmonella enterica subsp. enterica serovar choleraesuis str. scsa50. Full crystallographic information is available from OCA.

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