3obz

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[[Image:3obz.jpg|left|200px]]
 
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{{STRUCTURE_3obz| PDB=3obz | SCENE= }}
{{STRUCTURE_3obz| PDB=3obz | SCENE= }}
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===Crystal structure of human phytanoyl-COA dioxygenase phyhd1 2-oxoglutarate and iron complex===
===Crystal structure of human phytanoyl-COA dioxygenase phyhd1 2-oxoglutarate and iron complex===
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==Function==
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[[http://www.uniprot.org/uniprot/PHYD1_HUMAN PHYD1_HUMAN]] Isoform 1 has alpha-ketoglutarate-dependent dioxygenase activity. Does not show detectable activity towards fatty acid CoA thioesters. Is not expected to be active with phytanoyl CoA. Isoform 2 and isoform 3 probably lack enzyme activity.<ref>PMID:21530488</ref>
==About this Structure==
==About this Structure==
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3OBZ is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OBZ OCA].
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[[3obz]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OBZ OCA].
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==Reference==
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<references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: McDonough, M A.]]
[[Category: McDonough, M A.]]
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[[Category: Oxidoreductase]]
[[Category: Oxidoreductase]]
[[Category: Oxygenase]]
[[Category: Oxygenase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 1 09:50:56 2010''
 

Revision as of 08:20, 2 May 2013

Template:STRUCTURE 3obz

Contents

Crystal structure of human phytanoyl-COA dioxygenase phyhd1 2-oxoglutarate and iron complex

Function

[PHYD1_HUMAN] Isoform 1 has alpha-ketoglutarate-dependent dioxygenase activity. Does not show detectable activity towards fatty acid CoA thioesters. Is not expected to be active with phytanoyl CoA. Isoform 2 and isoform 3 probably lack enzyme activity.[1]

About this Structure

3obz is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Zhang Z, Kochan GT, Ng SS, Kavanagh KL, Oppermann U, Schofield CJ, McDonough MA. Crystal structure of PHYHD1A, a 2OG oxygenase related to phytanoyl-CoA hydroxylase. Biochem Biophys Res Commun. 2011 May 20;408(4):553-8. doi:, 10.1016/j.bbrc.2011.04.059. Epub 2011 Apr 21. PMID:21530488 doi:10.1016/j.bbrc.2011.04.059

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