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3ou5

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{{STRUCTURE_3ou5| PDB=3ou5 | SCENE= }}
{{STRUCTURE_3ou5| PDB=3ou5 | SCENE= }}
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===HUMAN MITOCHONDRIAL SERINE HYDROXYMETHYLTRANSFERASe 2===
===HUMAN MITOCHONDRIAL SERINE HYDROXYMETHYLTRANSFERASe 2===
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==Function==
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[[http://www.uniprot.org/uniprot/GLYM_HUMAN GLYM_HUMAN]] Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Required to prevent uracil accumulation in mtDNA. Interconversion of serine and glycine. Associates with mitochondrial DNA.<ref>PMID:21876188</ref>
==About this Structure==
==About this Structure==
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3OU5 is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2a7v 2a7v]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OU5 OCA].
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[[3ou5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2a7v 2a7v]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OU5 OCA].
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==Reference==
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<references group="xtra"/><references/>
[[Category: Glycine hydroxymethyltransferase]]
[[Category: Glycine hydroxymethyltransferase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Structural genomics consortium]]
[[Category: Structural genomics consortium]]
[[Category: Transferase]]
[[Category: Transferase]]
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Revision as of 08:23, 2 May 2013

Template:STRUCTURE 3ou5

Contents

HUMAN MITOCHONDRIAL SERINE HYDROXYMETHYLTRANSFERASe 2

Function

[GLYM_HUMAN] Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Required to prevent uracil accumulation in mtDNA. Interconversion of serine and glycine. Associates with mitochondrial DNA.[1]

About this Structure

3ou5 is a 1 chain structure with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 2a7v. Full crystallographic information is available from OCA.

Reference

  1. ↑ Anderson DD, Quintero CM, Stover PJ. Identification of a de novo thymidylate biosynthesis pathway in mammalian mitochondria. Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15163-8. doi:, 10.1073/pnas.1103623108. Epub 2011 Aug 26. PMID:21876188 doi:10.1073/pnas.1103623108

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