3par

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m (Protected "3par" [edit=sysop:move=sysop])
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[[Image:3par.png|left|200px]]
 
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{{STRUCTURE_3par| PDB=3par | SCENE= }}
{{STRUCTURE_3par| PDB=3par | SCENE= }}
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===Surfactant Protein-A neck and carbohydrate recognition domain (NCRD) in the absence of ligand===
===Surfactant Protein-A neck and carbohydrate recognition domain (NCRD) in the absence of ligand===
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{{ABSTRACT_PUBMED_21047777}}
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==Function==
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[[http://www.uniprot.org/uniprot/SFTPA_RAT SFTPA_RAT]] In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration.
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{{ABSTRACT_PUBMED_21047777}}
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==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:21047777</ref><references group="xtra"/>
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<ref group="xtra">PMID:021047777</ref><references group="xtra"/><references/>
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Cafarella, T M.]]
[[Category: Cafarella, T M.]]
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[[Category: Shang, F.]]
[[Category: Shang, F.]]
[[Category: Wu, H.]]
[[Category: Wu, H.]]
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[[Category: Carbohydrate binding]]
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[[Category: Collectin]]
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[[Category: Lectin]]
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[[Category: Mannose]]
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[[Category: Sugar binding protein]]

Revision as of 08:28, 2 May 2013

Template:STRUCTURE 3par

Contents

Surfactant Protein-A neck and carbohydrate recognition domain (NCRD) in the absence of ligand

Template:ABSTRACT PUBMED 21047777

Function

[SFTPA_RAT] In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air-liquid interface in the alveoli of the mammalian lung and is essential for normal respiration.

About this Structure

3par is a 1 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • Shang F, Rynkiewicz MJ, McCormack FX, Wu H, Cafarella TM, Head JF, Seaton BA. Crystallographic Complexes of Surfactant Protein A and Carbohydrates Reveal Ligand-induced Conformational Change. J Biol Chem. 2011 Jan 7;286(1):757-65. Epub 2010 Nov 3. PMID:21047777 doi:10.1074/jbc.M110.175265

Proteopedia Page Contributors and Editors (what is this?)

OCA

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