Taylor sandboxk ricin rRNA modification site
From Proteopedia
(Difference between revisions)
(New page: == Your Heading Here (maybe something like 'Structure') == <StructureSection load='1s72' size='400' side='right' caption='ribosomal RNA from Haloarcula(PDB entry 1s72)' scene=''> Ricin...) |
|||
| Line 1: | Line 1: | ||
| - | == | + | == Site of ricin modification of rRNA == |
<StructureSection load='1s72' size='400' side='right' caption='ribosomal RNA from Haloarcula(PDB entry [[1s72]])' scene=''> | <StructureSection load='1s72' size='400' side='right' caption='ribosomal RNA from Haloarcula(PDB entry [[1s72]])' scene=''> | ||
Ricin removes an adenine from a specific portion of the 28S rRNA. This modification leads to reduced | Ricin removes an adenine from a specific portion of the 28S rRNA. This modification leads to reduced | ||
| Line 5: | Line 5: | ||
While the structure of an eukaryotic ribosome is known, it is not at the level of detail to be able to precisely map this location. What is known about the location of the depurination is: | While the structure of an eukaryotic ribosome is known, it is not at the level of detail to be able to precisely map this location. What is known about the location of the depurination is: | ||
| - | --The depurination occurs in the sacrin-ricin loop of the 28S subunit at a GAGA sequence | + | --The depurination occurs in the sacrin-ricin loop of the 28S subunit at a GAGA sequence at A4324 (eukaryotic numbering) |
--L3 and L6 bind to this same loop | --L3 and L6 bind to this same loop | ||
</StructureSection> | </StructureSection> | ||
Revision as of 19:50, 3 May 2013
Site of ricin modification of rRNA
| |||||||||||
