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4jn6

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'''Unreleased structure'''
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{{STRUCTURE_4jn6| PDB=4jn6 | SCENE= }}
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===Crystal Structure of the Aldolase-Dehydrogenase Complex from Mycobacterium tuberculosis HRv37===
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{{ABSTRACT_PUBMED_23614353}}
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The entry 4jn6 is ON HOLD until Paper Publication
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==Function==
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[[http://www.uniprot.org/uniprot/HOA_MYCTU HOA_MYCTU]] Catalyzes the retro-aldol cleavage of 4-hydroxy-2-oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity). [[http://www.uniprot.org/uniprot/ACDH_MYCTU ACDH_MYCTU]] Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity).
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Authors: Carere, J., McKenna, S.E., Kimber, M.S., Seah, S.Y.K.
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==About this Structure==
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[[4jn6]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JN6 OCA].
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Description: Crystal Structure of the Aldolase-Dehydrogenase Complex from Mycobacterium tuberculosis HRv37
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[[Category: 4-hydroxy-2-oxovalerate aldolase]]
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Carere, J.]]
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[[Category: Kimber, M S.]]
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[[Category: McKenna, S E.]]
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[[Category: Seah, S Y.K.]]
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[[Category: Aldolase-dehydrogenase]]
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[[Category: Lyase-oxidoreductase complex]]
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[[Category: Rossmann fold]]
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[[Category: Tim barrel]]

Revision as of 07:45, 8 May 2013

Template:STRUCTURE 4jn6

Crystal Structure of the Aldolase-Dehydrogenase Complex from Mycobacterium tuberculosis HRv37

Template:ABSTRACT PUBMED 23614353

Function

[HOA_MYCTU] Catalyzes the retro-aldol cleavage of 4-hydroxy-2-oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity). [ACDH_MYCTU] Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds (By similarity).

About this Structure

4jn6 is a 4 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.

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OCA

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