3q41

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:3q41.jpg|left|200px]]
 
- 
-
<!--
 
-
The line below this paragraph, containing "STRUCTURE_3q41", creates the "Structure Box" on the page.
 
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
 
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
 
-
or leave the SCENE parameter empty for the default display.
 
-
-->
 
{{STRUCTURE_3q41| PDB=3q41 | SCENE= }}
{{STRUCTURE_3q41| PDB=3q41 | SCENE= }}
- 
===Crystal structure of the GluN1 N-terminal domain (NTD)===
===Crystal structure of the GluN1 N-terminal domain (NTD)===
 +
{{ABSTRACT_PUBMED_21389213}}
-
 
+
==Function==
-
<!--
+
[[http://www.uniprot.org/uniprot/NMDZ1_RAT NMDZ1_RAT]] NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. Plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors.<ref>PMID:15996549</ref>
-
The line below this paragraph, {{ABSTRACT_PUBMED_21389213}}, adds the Publication Abstract to the page
+
-
(as it appears on PubMed at http://www.pubmed.gov), where 21389213 is the PubMed ID number.
+
-
-->
+
-
{{ABSTRACT_PUBMED_21389213}}
+
==About this Structure==
==About this Structure==
Line 22: Line 10:
==Reference==
==Reference==
-
<ref group="xtra">PMID:21389213</ref><references group="xtra"/>
+
<ref group="xtra">PMID:021389213</ref><references group="xtra"/><references/>
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Blain, K Y.]]
[[Category: Blain, K Y.]]
Line 30: Line 18:
[[Category: Maruo, T.]]
[[Category: Maruo, T.]]
[[Category: Nakagawa, T.]]
[[Category: Nakagawa, T.]]
 +
[[Category: Glun1]]
 +
[[Category: Glycosylation]]
 +
[[Category: Ion channel]]
 +
[[Category: Nmda]]
 +
[[Category: Ntd]]
 +
[[Category: Transport protein]]

Revision as of 08:09, 8 May 2013

Template:STRUCTURE 3q41

Contents

Crystal structure of the GluN1 N-terminal domain (NTD)

Template:ABSTRACT PUBMED 21389213

Function

[NMDZ1_RAT] NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. Plays a key role in synaptic plasticity, synaptogenesis, excitotoxicity, memory acquisition and learning. It mediates neuronal functions in glutamate neurotransmission. Is involved in the cell surface targeting of NMDA receptors.[1]

About this Structure

3q41 is a 3 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • Farina AN, Blain KY, Maruo T, Kwiatkowski W, Choe S, Nakagawa T. Separation of Domain Contacts Is Required for Heterotetrameric Assembly of Functional NMDA Receptors. J Neurosci. 2011 Mar 9;31(10):3565-79. PMID:21389213 doi:10.1523/JNEUROSCI.6041-10.2011
  1. ↑ Inanobe A, Furukawa H, Gouaux E. Mechanism of partial agonist action at the NR1 subunit of NMDA receptors. Neuron. 2005 Jul 7;47(1):71-84. PMID:15996549 doi:10.1016/j.neuron.2005.05.022

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/3q41"
Personal tools