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3pnb

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[[Image:3pnb.jpg|left|200px]]
 
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{{STRUCTURE_3pnb| PDB=3pnb | SCENE= }}
{{STRUCTURE_3pnb| PDB=3pnb | SCENE= }}
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===Phosphopantetheine Adenylyltransferase from Mycobacterium tuberculosis in complex with coenzyme A===
===Phosphopantetheine Adenylyltransferase from Mycobacterium tuberculosis in complex with coenzyme A===
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{{ABSTRACT_PUBMED_21543857}}
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==Function==
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[[http://www.uniprot.org/uniprot/COAD_MYCTU COAD_MYCTU]] Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity).
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(as it appears on PubMed at http://www.pubmed.gov), where 21543857 is the PubMed ID number.
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{{ABSTRACT_PUBMED_21543857}}
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==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:021543857</ref><references group="xtra"/>
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<ref group="xtra">PMID:021543857</ref><references group="xtra"/><references/>
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Pantetheine-phosphate adenylyltransferase]]
[[Category: Pantetheine-phosphate adenylyltransferase]]

Revision as of 08:14, 8 May 2013

Template:STRUCTURE 3pnb

Contents

Phosphopantetheine Adenylyltransferase from Mycobacterium tuberculosis in complex with coenzyme A

Template:ABSTRACT PUBMED 21543857

Function

[COAD_MYCTU] Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity).

About this Structure

3pnb is a 4 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.

Reference

  • Wubben T, Mesecar AD. Structure of Mycobacterium tuberculosis phosphopantetheine adenylyltransferase in complex with the feedback inhibitor CoA reveals only one active-site conformation. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2011 May 1;67(Pt, 5):541-5. Epub 2011 Apr 20. PMID:21543857 doi:10.1107/S1744309111010761

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