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3pv9
From Proteopedia
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m (Protected "3pv9" [edit=sysop:move=sysop]) |
Revision as of 08:15, 8 May 2013
Structure of PH1245, a cas1 from Pyrococcus horikoshii
Function
[O58938_PYRHO] CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity).[HAMAP-Rule:MF_01470]
About this Structure
3pv9 is a 2 chain structure with sequence from Pyrococcus horikoshii. Full crystallographic information is available from OCA.
