3q0r
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | [[Image:3q0r.jpg|left|200px]] | ||
| - | |||
| - | <!-- | ||
| - | The line below this paragraph, containing "STRUCTURE_3q0r", creates the "Structure Box" on the page. | ||
| - | You may change the PDB parameter (which sets the PDB file loaded into the applet) | ||
| - | or the SCENE parameter (which sets the initial scene displayed when the page is loaded), | ||
| - | or leave the SCENE parameter empty for the default display. | ||
| - | --> | ||
{{STRUCTURE_3q0r| PDB=3q0r | SCENE= }} | {{STRUCTURE_3q0r| PDB=3q0r | SCENE= }} | ||
| - | |||
===Crystal structure of the PUMILIO-homology domain from Human PUMILIO2 in complex with p38alpha NREb=== | ===Crystal structure of the PUMILIO-homology domain from Human PUMILIO2 in complex with p38alpha NREb=== | ||
| + | {{ABSTRACT_PUBMED_021397187}} | ||
| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/PUM2_HUMAN PUM2_HUMAN]] Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of mRNA targets. Its interactions and tissue specificity suggest that it may be required to support proliferation and self-renewal of stem cells by regulating the translation of key transcripts. | ||
==About this Structure== | ==About this Structure== | ||
| Line 17: | Line 11: | ||
[[Category: Hall, T M.T.]] | [[Category: Hall, T M.T.]] | ||
[[Category: Lu, G.]] | [[Category: Lu, G.]] | ||
| + | [[Category: Gene regulation]] | ||
| + | [[Category: Puf]] | ||
| + | [[Category: Pumilio-homolgy domain]] | ||
| + | [[Category: Rna binding]] | ||
| + | [[Category: Rna binding protein-rna complex]] | ||
Revision as of 08:17, 8 May 2013
Crystal structure of the PUMILIO-homology domain from Human PUMILIO2 in complex with p38alpha NREb
Template:ABSTRACT PUBMED 021397187
Function
[PUM2_HUMAN] Sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding the 3'-UTR of mRNA targets. Its interactions and tissue specificity suggest that it may be required to support proliferation and self-renewal of stem cells by regulating the translation of key transcripts.
About this Structure
3q0r is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
