3poa
From Proteopedia
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{{STRUCTURE_3poa| PDB=3poa | SCENE= }} | {{STRUCTURE_3poa| PDB=3poa | SCENE= }} | ||
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===Structural and functional analysis of phosphothreonine-dependent FHA domain interactions=== | ===Structural and functional analysis of phosphothreonine-dependent FHA domain interactions=== | ||
| + | {{ABSTRACT_PUBMED_21134638}} | ||
| - | + | ==Function== | |
| - | + | [[http://www.uniprot.org/uniprot/P71590_MYCTU P71590_MYCTU]] Regulates cell growth and peptidoglycan synthesis by binding to MviN. May inhibit the late stages of peptidoglycan synthesis.<ref>PMID:22275220</ref> | |
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==About this Structure== | ==About this Structure== | ||
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==Reference== | ==Reference== | ||
| - | <ref group="xtra">PMID: | + | <ref group="xtra">PMID:021134638</ref><references group="xtra"/><references/> |
[[Category: Mycobacterium tuberculosis]] | [[Category: Mycobacterium tuberculosis]] | ||
[[Category: Pennell, S.]] | [[Category: Pennell, S.]] | ||
[[Category: Smerdon, S J.]] | [[Category: Smerdon, S J.]] | ||
| + | [[Category: Fha domain]] | ||
| + | [[Category: Peptide binding protein]] | ||
| + | [[Category: Synthetic phosphopeptide]] | ||
Revision as of 08:19, 8 May 2013
Contents |
Structural and functional analysis of phosphothreonine-dependent FHA domain interactions
Template:ABSTRACT PUBMED 21134638
Function
[P71590_MYCTU] Regulates cell growth and peptidoglycan synthesis by binding to MviN. May inhibit the late stages of peptidoglycan synthesis.[1]
About this Structure
3poa is a 2 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.
Reference
- Pennell S, Westcott S, Ortiz-Lombardia M, Patel D, Li J, Nott TJ, Mohammed D, Buxton RS, Yaffe MB, Verma C, Smerdon SJ. Structural and functional analysis of phosphothreonine-dependent FHA domain interactions. Structure. 2010 Dec 8;18(12):1587-95. PMID:21134638 doi:10.1016/j.str.2010.09.014
- ↑ Gee CL, Papavinasasundaram KG, Blair SR, Baer CE, Falick AM, King DS, Griffin JE, Venghatakrishnan H, Zukauskas A, Wei JR, Dhiman RK, Crick DC, Rubin EJ, Sassetti CM, Alber T. A phosphorylated pseudokinase complex controls cell wall synthesis in mycobacteria. Sci Signal. 2012 Jan 24;5(208):ra7. PMID:22275220 doi:10.1126/scisignal.2002525
