3pm6

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[[Image:3pm6.png|left|200px]]
 
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{{STRUCTURE_3pm6| PDB=3pm6 | SCENE= }}
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===Crystal structure of a putative fructose-1,6-biphosphate aldolase from Coccidioides immitis solved by combined SAD MR===
===Crystal structure of a putative fructose-1,6-biphosphate aldolase from Coccidioides immitis solved by combined SAD MR===
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{{ABSTRACT_PUBMED_21359836}}
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==Function==
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[[http://www.uniprot.org/uniprot/ALF_COCIM ALF_COCIM]] Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis (By similarity).
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{{ABSTRACT_PUBMED_21359836}}
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==About this Structure==
==About this Structure==
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==Reference==
==Reference==
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<ref group="xtra">PMID:021359836</ref><references group="xtra"/>
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<ref group="xtra">PMID:021359836</ref><references group="xtra"/><references/>
[[Category: Coccidioides immitis]]
[[Category: Coccidioides immitis]]
[[Category: Fructose-bisphosphate aldolase]]
[[Category: Fructose-bisphosphate aldolase]]

Revision as of 08:22, 8 May 2013

Template:STRUCTURE 3pm6

Contents

Crystal structure of a putative fructose-1,6-biphosphate aldolase from Coccidioides immitis solved by combined SAD MR

Template:ABSTRACT PUBMED 21359836

Function

[ALF_COCIM] Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis (By similarity).

About this Structure

3pm6 is a 2 chain structure with sequence from Coccidioides immitis. Full crystallographic information is available from OCA.

Reference

  • Abendroth J, Gardberg AS, Robinson JI, Christensen JS, Staker BL, Myler PJ, Stewart LJ, Edwards TE. SAD phasing using iodide ions in a high-throughput structural genomics environment. J Struct Funct Genomics. 2011 Jul;12(2):83-95. Epub 2011 Feb 27. PMID:21359836 doi:10.1007/s10969-011-9101-7

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OCA

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