3pp2
From Proteopedia
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{{STRUCTURE_3pp2| PDB=3pp2 | SCENE= }} | {{STRUCTURE_3pp2| PDB=3pp2 | SCENE= }} | ||
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===Crystal structure of the pleckstrin homology domain of ArhGAP27=== | ===Crystal structure of the pleckstrin homology domain of ArhGAP27=== | ||
+ | ==Function== | ||
+ | [[http://www.uniprot.org/uniprot/RHG27_HUMAN RHG27_HUMAN]] Rho GTPase-activating protein which may be involved in clathrin-mediated endocytosis. GTPase activators for the Rho-type GTPases act by converting them to an inactive GDP-bound state. Has activity toward CDC42 and RAC1 (By similarity). | ||
==About this Structure== | ==About this Structure== | ||
- | + | [[3pp2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PP2 OCA]. | |
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Arrowsmith, C H.]] | [[Category: Arrowsmith, C H.]] | ||
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[[Category: Sgc]] | [[Category: Sgc]] | ||
[[Category: Structural genomics consortium]] | [[Category: Structural genomics consortium]] | ||
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- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 8 11:55:22 2010'' |
Revision as of 08:23, 8 May 2013
Crystal structure of the pleckstrin homology domain of ArhGAP27
Function
[RHG27_HUMAN] Rho GTPase-activating protein which may be involved in clathrin-mediated endocytosis. GTPase activators for the Rho-type GTPases act by converting them to an inactive GDP-bound state. Has activity toward CDC42 and RAC1 (By similarity).
About this Structure
3pp2 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Categories: Homo sapiens | Arrowsmith, C H. | Bountra, C. | Edwards, A M. | Li, Y. | Nedyalkova, L. | Park, H. | SGC, Structural Genomics Consortium. | Shen, L. | Tempel, W. | Tong, Y. | Weigelt, J. | Wernimont, A K. | Gtpase activator | Hydrolase activator | Ph domain | Pleckstrin homology domain | Sgc | Structural genomics consortium