3psn
From Proteopedia
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{{STRUCTURE_3psn| PDB=3psn | SCENE= }} | {{STRUCTURE_3psn| PDB=3psn | SCENE= }} | ||
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===Crystal structure of mouse VPS29 complexed with Mn2+=== | ===Crystal structure of mouse VPS29 complexed with Mn2+=== | ||
| + | ==Function== | ||
| + | [[http://www.uniprot.org/uniprot/VPS29_MOUSE VPS29_MOUSE]] Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro). | ||
==About this Structure== | ==About this Structure== | ||
| - | + | [[3psn]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3lh7 3lh7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PSN OCA]. | |
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: Phosphoserine phosphatase]] | [[Category: Phosphoserine phosphatase]] | ||
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[[Category: Tbc1d5]] | [[Category: Tbc1d5]] | ||
[[Category: Vps35]] | [[Category: Vps35]] | ||
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 15 08:35:53 2010'' | ||
Revision as of 08:32, 8 May 2013
Crystal structure of mouse VPS29 complexed with Mn2+
Function
[VPS29_MOUSE] Essential component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Also required to regulate transcytosis of the polymeric immunoglobulin receptor (pIgR-pIgA). Has low protein phosphatase activity towards a serine-phosphorylated peptide derived from IGF2R (in vitro) (By similarity). Has no activity towards p-nitrophenylphosphate, p-nitrophenylphosphorylcholine or phosphatidylinositlphosphates (in vitro).
About this Structure
3psn is a 2 chain structure with sequence from Mus musculus. This structure supersedes the now removed PDB entry 3lh7. Full crystallographic information is available from OCA.
